Broad spectrum structure discovery in large-scale higher-order networks

Journal Article (2026)
Author(s)

John Hood (University of Chicago)

C. De Bacco (TU Delft - Electrical Engineering, Mathematics and Computer Science)

Aaron Schein (University of Chicago)

Research Group
Network Architectures and Services
DOI related publication
https://doi.org/10.1038/s41467-026-71903-0 Final published version
More Info
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Publication Year
2026
Language
English
Research Group
Network Architectures and Services
Journal title
Nature Communications
Issue number
1
Volume number
17
Article number
5765
Downloads counter
14
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Abstract

Complex systems are often driven by higher-order interactions among multiple units, naturally represented as hypergraphs. Understanding dependency structures within these hypergraphs is crucial for understanding and predicting the behavior of complex systems but is made challenging by their combinatorial complexity and computational demands. In this paper, we introduce a class of probabilistic models that efficiently represents and discovers a broad spectrum of mesoscale structure in large-scale hypergraphs. The key insight enabling this approach is to treat classes of similar units as themselves nodes in a latent hypergraph. By modeling observed node interactions through latent interactions among classes using low-rank representations, our approach tractably captures rich structural patterns while ensuring model identifiability. This allows for direct interpretation of distinct node- and class-level structures. Empirically, our model improves link prediction over state-of-the-art methods and discovers interpretable structures in diverse real-world systems, including pharmacological and social networks, advancing our ability to incorporate large-scale higher-order data into the scientific process.