Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging
Tianshi Wang (Erasmus MC)
Tom Pfeiffer (University of Lübeck)
Joost Daemen (Erasmus MC)
Frits Mastik (Erasmus MC)
Wolfgang Wieser (Optores GmbH)
A. F.W. Van Der Steen (Chinese Academy of Sciences, ImPhys/Acoustical Wavefield Imaging , Erasmus MC)
Robert Huber (University of Lübeck)
Gijs Van Soest (Erasmus MC)
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Abstract
We demonstrate megahertz intravascular Doppler Optical Coherence Tomography (OCT). The OCT system relies on a 1.1 mm diameter motorized catheter and a 1.5 MHz Fourier Domain Mode Locked (FDML) laser. By resolving the phase shift between adjoint A-lines, the flow pattern image can be reconstructed. Imaging experiments were carried out in swine coronary artery in vitro at a speed of 600 frames/s. The MHz sweep rate not only allows us to investigate flow velocity of up to 37.5 cm/s without phase-unwrapping, but also enables dynamic flow imaging at high frame rate.
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