Print Email Facebook Twitter Image Acquisition and Attenuation Map Estimation for Multi-pinhole Clinical SPECT Title Image Acquisition and Attenuation Map Estimation for Multi-pinhole Clinical SPECT Author Chen, Y. (TU Delft RST/Biomedical Imaging) Contributor Beekman, F.J. (promotor) Goorden, M.C. (copromotor) Degree granting institution Delft University of Technology Date 2021-07-13 Abstract Single-photon emission computed tomography (SPECT) is a well-established nuclear imaging modality for studying functional and pathological properties of the brain. Conventional general purpose SPECT systems typically offer a spatial resolution of about 10 mm with a sensitivity of 0.01-0.02%. A few dedicated brain SPECT scanners have been proposed, but resolutions and sensitivities are no better than 7 mm and 0.03% respectively, and some of these scanners are not manufactured anymore. This limited resolution hampers detection of localized brain abnormalities, while the low sensitivity requires a long scanning time that limits fast dynamic studies. Besides a compromised resolution and sensitivity, conventional SPECT systems require rotation of heavy detectors to obtain sufficient angular projections, which hamper fast dynamic imaging. Subject brain SPECTpinhole collimationDaTscansufficient samplingconvolutional neural networkMonte Carlo simulation To reference this document use: https://doi.org/10.4233/uuid:49102b45-50fc-4d17-a38b-eb9de43f6c1e ISBN 978-94-6384-232-7 Part of collection Institutional Repository Document type doctoral thesis Rights © 2021 Y. Chen Files PDF thesis_Y.Chen_all.pdf 37.38 MB Close viewer /islandora/object/uuid:49102b45-50fc-4d17-a38b-eb9de43f6c1e/datastream/OBJ/view