Print Email Facebook Twitter Dynamic Light Scattering Title Dynamic Light Scattering: A New Noninvasive Technology for Neonatal Heart Rate Monitoring Author Gangaram-Panday, Norani H. (Erasmus MC) van Essen, Tanja (Erasmus MC) Goos, T.G. (TU Delft Medical Instruments & Bio-Inspired Technology; Erasmus MC) De Jonge, Rogier C.J. (Erasmus MC) Reiss, Irwin K.M. (Erasmus MC) van Weteringen, Willem (Erasmus MC) Date 2020 Abstract Heart rate (HR) detection in premature infants using electrocardiography (ECG) is challenging due to a low signal amplitude and the fragility of the premature skin. Recently, the dynamic light scattering (DLS) technique has been miniaturized, allowing noninvasive HR measurements with a single sensor. Objective: The aim was to determine the accuracy of DLS for HR measurement in infants, compared to ECG-derived HR. Methods: Stable infants with a gestational age of ≥26 weeks, monitored with ECG, were eligible for inclusion. HR was measured with the DLS sensor at 5 different sites for 15 min each. We recorded every 10th second of the DLS-derived HR and the DLS signal-to-noise ratio (SNR), and the ECG-derived HR was extracted for analysis. Patients were randomly divided into 2 groups. In the first group, the optimal SNR cut-off value was determined and then applied to the second group to assess agreement. Results: HR measurements from 31 infants were analyzed. ECG-DLS paired data points were collected at the forehead, an upper extremity, the thorax, a lower extremity, and the abdomen. When applying the international accuracy standard for HR detection, DLS accuracy in the first group (n = 15) was optimal at the forehead (SNR cut-off 1.66). Application of this cut-off to the second group (n = 16) showed good agreement between DLS-derived HR and ECG-derived HR (bias –0.73 bpm; 95% limits of agreement –15.46 and 14.00 bpm) at the forehead with approximately 80% (i.e., 1,066/1,310) of all data pairs remaining. Conclusion: The investigated DLS sensor was sensitive to movement, overall providing less accurate HR measurements than ECG and pulse oximetry. In this study population, specific measurement sites provided excellent signal quality and good agreement with ECG-derived HR. Subject Noninvasive measurementDynamic light scatteringNeonateHeart rateSensor To reference this document use: http://resolver.tudelft.nl/uuid:6c291877-8907-4e03-b4fe-c28bcd0aea8c DOI https://doi.org/10.1159/000506771 ISSN 1661-7819 Source Neonatology, 117 (3), 279-286 Part of collection Institutional Repository Document type journal article Rights © 2020 Norani H. Gangaram-Panday, Tanja van Essen, T.G. Goos, Rogier C.J. De Jonge, Irwin K.M. Reiss, Willem van Weteringen Files PDF 506771_1.pdf 903.45 KB Close viewer /islandora/object/uuid:6c291877-8907-4e03-b4fe-c28bcd0aea8c/datastream/OBJ/view