Print Email Facebook Twitter Biodegradation and mechanical behavior of an advanced bioceramic-containing Mg matrix composite synthesized through in-situ solid-state oxidation Title Biodegradation and mechanical behavior of an advanced bioceramic-containing Mg matrix composite synthesized through in-situ solid-state oxidation Author Naddaf Dezfuli, S. (TU Delft (OLD) MSE-1) Brouwer, J.C. (TU Delft (OLD) MSE-1) Mol, J.M.C. (TU Delft (OLD) MSE-6) van der Helm, F.C.T. (TU Delft Biomechatronics & Human-Machine Control) Zhou, J. (TU Delft Biomaterials & Tissue Biomechanics) Date 2018 Abstract Recent studies have shown great potential of Mg matrix composites for biodegradable orthopedic devices. However, the poor structural integrity of these composites, which results in excessive localized corrosion and premature mechanical failure, has hindered their widespread applications. In this research, an in-situ Powder Metallurgy (PM) method was used to fabricate a novel biodegradable Mg-bredigite composite and to achieve enhanced chemical interfacial locking between the constituents by triggering a solid-state thermochemical reaction between Mg and bredigite particles. The reaction resulted in a highly densified and integrated microstructure, which prevented corrosion pits from propagating when the composite was immersed in a physiological solution. In addition, chemical interlocking between the constituents prohibited interparticle fracture and subsequent surface delamination during compression testing, enabling the composite to withstand larger plastic deformation before mechanical failure. Furthermore, the composite was proven to be biocompatible and capable of maintaining its ultimate compressive strength in the strength range of cortical bone after 25-day immersion in DMEM. The research provided the necessary information to guide further research towards the development of a next generation of biodegradable Mg matrix composites with enhanced chemical interlocking. Subject BiocompatibilityChemical interlockingCompositeDegradationMagnesiumMechanical property To reference this document use: http://resolver.tudelft.nl/uuid:7b88ee07-366a-4289-9365-24c410412313 DOI https://doi.org/10.1016/j.jmbbm.2018.01.014 Embargo date 2018-09-01 ISSN 1751-6161 Source Journal of the Mechanical Behavior of Biomedical Materials, 80, 209-221 Bibliographical note Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public. Part of collection Institutional Repository Document type journal article Rights © 2018 S. Naddaf Dezfuli, J.C. Brouwer, J.M.C. Mol, F.C.T. van der Helm, J. Zhou Files PDF 1_s2.0_S1751616118300183_main.pdf 2.53 MB Close viewer /islandora/object/uuid:7b88ee07-366a-4289-9365-24c410412313/datastream/OBJ/view