Print Email Facebook Twitter Computer-Aided Diagnosis and Prediction in Brain Disorders Title Computer-Aided Diagnosis and Prediction in Brain Disorders Author Venkatraghavan, Vikram (Vrije Universiteit Amsterdam; Amsterdam Neuroscience, Neurodegeneration) Voort, Sebastian R.van der (Erasmus MC) Bos, Daniel (Erasmus MC) Smits, M. (Erasmus MC) Barkhof, Frederik (University College London; Amsterdam UMC) Niessen, W.J. (TU Delft ImPhys/Vos group; TU Delft ImPhys/Computational Imaging; Erasmus MC) Klein, Stefan (Erasmus MC) Bron, Esther E. (Erasmus MC) Contributor Colliot, O. (editor) Date 2023 Abstract Computer-aided methods have shown added value for diagnosing and predicting brain disorders and can thus support decision making in clinical care and treatment planning. This chapter will provide insight into the type of methods, their working, their input data –such as cognitive tests, imaging, and genetic data– and the types of output they provide. We will focus on specific use cases for diagnosis, i.e., estimating the current “condition” of the patient, such as early detection and diagnosis of dementia, differential diagnosis of brain tumors, and decision making in stroke. Regarding prediction, i.e., estimation of the future “condition” of the patient, we will zoom in on use cases such as predicting the disease course in multiple sclerosis and predicting patient outcomes after treatment in brain cancer. Furthermore, based on these use cases, we will assess the current state-of-the-art methodology and highlight current efforts on benchmarking of these methods and the importance of open science therein. Finally, we assess the current clinical impact of computer-aided methods and discuss the required next steps to increase clinical impact. Subject Cognitive impairmentDementiaGliomaStroke To reference this document use: http://resolver.tudelft.nl/uuid:ef5974e4-e603-42ac-914c-281d36acad2a DOI https://doi.org/10.1007/978-1-0716-3195-9_15 Publisher Humana Press Inc. ISBN 978-1-0716-3194-2 Source Machine Learning for Brain Disorders Series Neuromethods, 0893-2336, 197 Part of collection Institutional Repository Document type book chapter Rights © 2023 Vikram Venkatraghavan, Sebastian R.van der Voort, Daniel Bos, M. Smits, Frederik Barkhof, W.J. Niessen, Stefan Klein, Esther E. Bron Files PDF 978_1_0716_3195_9_15.pdf 1.11 MB Close viewer /islandora/object/uuid:ef5974e4-e603-42ac-914c-281d36acad2a/datastream/OBJ/view