Print Email Facebook Twitter Food anticipatory hormonal responses Title Food anticipatory hormonal responses: A systematic review of animal and human studies Author Skvortsova, Aleksandrina (Universiteit Leiden; McGill University) Veldhuijzen, Dieuwke S. (Universiteit Leiden) Kloosterman, Iris E.M. (Universiteit Leiden) Pacheco-López, Gustavo (Universiteit Leiden; Metropolitan Autonomous University, Lerma de Villada) Evers, A.W.M. (TU Delft Applied Ergonomics and Design; TU Delft HR Health; Universiteit Leiden; Erasmus Universiteit Rotterdam) Date 2021 Abstract Food anticipatory hormonal responses (cephalic responses) are proactive physiological processes, that allow animals to prepare for food ingestion by modulating their hormonal levels in response to food cues. This process is important for digesting food, metabolizing nutrients and maintaining glucose levels within homeostasis. In this systematic review, we summarize the evidence from animal and human research on cephalic responses. Thirty-six animal and fifty-three human studies were included. The majority (88 %) of studies demonstrated that hormonal levels are changed in response to cues previously associated with food intake, such as feeding time, smell, and sight of food. Most evidence comes from studies on insulin, ghrelin, pancreatic polypeptide, glucagon, and c-peptide. Moreover, impaired cephalic responses were found in disorders related to metabolism and food intake such as diabetes, pancreatic insufficiency, obesity, and eating disorders, which opens discussions about the etiological mechanisms of these disorders as well as on potential therapeutic opportunities. Subject Anticipatory hormone releaseCephalic responsesFood To reference this document use: http://resolver.tudelft.nl/uuid:4bd9d0da-9cf5-4fd5-958a-b39ca934dd04 DOI https://doi.org/10.1016/j.neubiorev.2021.03.030 ISSN 0149-7634 Source Neuroscience and Biobehavioral Reviews, 126, 447-464 Part of collection Institutional Repository Document type review Rights © 2021 Aleksandrina Skvortsova, Dieuwke S. Veldhuijzen, Iris E.M. Kloosterman, Gustavo Pacheco-López, A.W.M. Evers Files PDF 1_s2.0_S0149763421001470_main.pdf 3.66 MB Close viewer /islandora/object/uuid:4bd9d0da-9cf5-4fd5-958a-b39ca934dd04/datastream/OBJ/view