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Bakhshaee Babaroud, N. (author), Rice, S.J. (author), Camarena, M. (author), Serdijn, W.A. (author), Vollebregt, S. (author), Giagka, Vasiliki (author)
In this paper, we present the surface modification of multilayer graphene electrodes with platinum (Pt) nanoparticles (NPs) using spark ablation. This method yields an individually selective local printing of NPs on an electrode surface at room temperature in a dry process. NP printing is performed as a post-process step to enhance the...
journal article 2024
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Rout, Samprajani (author), Monna, G.L.E. (author), Pareschi, Fabio (author), Setti, Gianluca (author), Serdijn, W.A. (author)
The key challenges in designing a multi-channel biosignal acquisition system for an ambulatory or invasive medical application with a high channel count are reducing the power consumption, area consumption and the outgoing wire count. This article proposes a spread-spectrum modulated biosignal acquisition system using a shared amplifier and...
journal article 2023
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Safarpour, Amin (author), Dehnavi, Farzaneh (author), Saberi, Mehdi (author), Lotfi, R. (author), Serdijn, W.A. (author)
In multi-electrode arrays (MEAs), for electrical recording and electrical stimulation, high voltage (HV) switches are employed to build an analog multiplexer to conduct either a HV stimulation signal from the pulse generator circuit to an electrode or a low-voltage noise-sensitive signal from the electrode to a recording stage. In this brief,...
journal article 2022
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Varkevisser, F. (author), Lopes Marta da Costa, T.M. (author), Serdijn, W.A. (author)
Power efficiency in electrical stimulator circuits is crucial for developing large-scale multichannel applications like bidirectional brain-computer interfaces and neuroprosthetic devices. Many state-of-the-art papers have suggested that some non-rectangular pulse shapes are more energy-efficient for exciting neural excitation than the...
journal article 2022
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Siddiqi, M.A. (author), Hahn, Georg (author), Hamdioui, S. (author), Serdijn, W.A. (author), Strydis, C. (author)
A Medical Body Area Network (MBAN) is an ensemble of collaborating, potentially heterogeneous, medical devices located inside, on the surface of or around the human body with the objective of tackling one or multiple medical conditions of the MBAN host. These devices-which are a special category of Wireless Body Area Networks (WBANs)–collect,...
journal article 2022
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Bakhshaee Babaroud, N. (author), Palmar, M. (author), Velea, A. (author), Coletti, C. (author), Weingärtner, S.D. (author), Vos, F.M. (author), Serdijn, W.A. (author), Vollebregt, S. (author), Giagka, Vasiliki (author)
Multimodal platforms combining electrical neural recording and stimulation, optogenetics, optical imaging, and magnetic resonance (MRI) imaging are emerging as a promising platform to enhance the depth of characterization in neuroscientific research. Electrically conductive, optically transparent, and MRI-compatible electrodes can optimally...
journal article 2022
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Coolen, R.J.J. (author), Emmer, K.M. (author), Spantidea, P.I. (author), Asselt, E. van (author), Scheepe, J.R. (author), Serdijn, W.A. (author), Blok, B.F.M. (author)
The first two objectives were to establish which stimulation parameters of kilohertz frequency alternating current (KHFAC) neuromodulation influence the effectiveness of pudendal nerve block and its safety. The third aim was to determine whether KHFAC neuromodulation of the pudendal nerve can relax the pelvic musculature, including the anal...
journal article 2022
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Coolen, R.L. (author), Emmer, K.M. (author), Spantidea, P.I. (author), Asselt, E. van (author), Scheepe, J.R. (author), Serdijn, W.A. (author), Blok, B.F.M. (author)
Hoogfrequente stimulatie met bifasische blokpulsen in de kHz-range induceert een tijdelijke zenuwgeleidingsblokkade. Toegepast op de nervus pudendus, kan het de bekkenmusculatuur ontspannen. Dit kan helpen bij het legen van de blaas en de darmen, hetgeen een nieuwe therapie biedt voor urineretentie en disfunctionele defecatie. Deze studie is...
journal article 2021
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Martins Da Ponte, R. (author), Gaio, N. (author), van Zeijl, H.W. (author), Vollebregt, S. (author), Dijkstra, Paul (author), Dekker, R. (author), Serdijn, W.A. (author), Giagka, Vasiliki (author)
One of the many applications of organ-on-a-chip (OOC) technology is the study of biological processes in human induced pluripotent stem cells (iPSCs) during pharmacological drug screening. It is of paramount importance to construct OOCs equipped with highly compact in situ sensors that can accurately monitor, in real time, the extracellular...
journal article 2021
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de Goederen, R. (author), Pu, S. (author), Silos Viu, M. (author), Doan, D. (author), Overeem, S. (author), Serdijn, W.A. (author), Joosten, K. F.M. (author), Long, X. (author), Dudink, J. (author)
Study objectives: Unobtrusive monitoring of sleep and sleep disorders in children presents challenges. We investigated the possibility of using Ultra-Wide band (UWB) radar to measure sleep in children. Methods: Thirty-two children scheduled to undergo a clinical polysomnography participated; their ages ranged from 2 months to 14 years. During...
journal article 2021
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Akgün, O.C. (author), Nanbakhsh, K. (author), Giagka, Vasiliki (author), Serdijn, W.A. (author)
For mm-sized implants incorporating silicon integrated circuits, ensuring lifetime operation of the chip within the corrosive environment of the body still remains a critical challenge. For the chip's packaging, various polymeric and thin ceramic coatings have been reported, demonstrating high biocompatibility and barrier properties. Yet, for...
journal article 2020
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Siddiqi, M.A. (author), Serdijn, W.A. (author), Strydis, C. (author)
The wireless capabilities of modern Implantable Medical Devices (IMDs) make them vulnerable to security attacks. One prominent attack, which has disastrous consequences for the patient’s wellbeing, is the battery Denial-of-Service attack whereby the IMD is occupied with continuous authentication requests from an adversary with the aim of...
journal article 2020
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Urso, A. (author), Chen, Y. (author), Staszewski, R.B. (author), Dijkhuis, Johan F. (author), Stanzione, Stefano (author), Liu, Y. (author), Serdijn, W.A. (author), Babaie, M. (author)
In this paper, we propose a new scheme to directly power a 4.9-5.6GHz LC oscillator from a recursive switched-capacitor DC-DC converter. A finite-state machine is integrated to automatically adjust the conversion ratio and switching frequency of the converter such that its DC output voltage is within ±5% of the desired 1V across input voltage...
journal article 2020
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Urso, A. (author), Chen, Y. (author), Dijkhuis, Johan F. (author), Liu, Yao-Hong (author), Babaie, M. (author), Serdijn, W.A. (author)
This article presents guidelines for designing the power supply blocks of RF oscillators. To preserve their spectral purity, the requirements on the noise and ripple of the supply voltage are firstly evaluated based on the oscillator supply pushing factor and the oscillator Figure-of-Merit (FOM). Those specifications are then employed to design...
journal article 2020
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Urso, A. (author), Giagka, Vasiliki (author), van Dongen, M.N. (author), Serdijn, W.A. (author)
In order to recruit neurons in excitable tissue, constant current neural stimulators are commonly used. Recently, ultra high-frequency (UHF) stimulation has been proposed and proven to have the same efficacy as constant-current stimulation. UHF stimulation uses a fundamentally different way of activating the tissue: each stimulation phase is...
journal article 2019
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Urso, A. (author), Giagka, Vasiliki (author), Serdijn, W.A. (author)
This manuscript points out some mistakes in the Introduction and in the table of comparison of a paper already published in this journal by Hsu and Schmid [1]. Although the main claim of [1] is still preserved, we believe the paper needs to be rectified for scientific correctness of the work. In [1], the first High Frequency Switched...
journal article 2019
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Giagka, Vasiliki (author), Serdijn, W.A. (author)
Patients suffering from conditions such as paralysis, diabetes or rheumatoid arthritis could in the future be treated in a personalised manner using bioelectronic medicines (BEms) (Nat Rev Drug Discov 13:399–400, 2013, Proc Natl Acad Sci USA 113:8284–9, 2016, J Intern Med 282:37–45, 2017). To deliver this personalised therapy based on...
journal article 2018
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Rezaeiyan, Y. (author), Zamani, M. (author), Shoaei, Omid (author), Serdijn, W.A. (author)
There is an increasing demand for low power, low voltage, and small size analog readout bio-potential systems. This paper presents an analog front-end for measuring the intra-cardiac signals in implantable and also external ambulatory ECG cardiac recording applications. The analog front-end benefits from voltage to frequency conversion...
journal article 2018
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Rezaeiyan, Y. (author), Zamani, M. (author), Shoaei, Omid (author), Serdijn, W.A. (author)
A low-power mixed-signal IC for implantable pacemakers is presented. The proposed system features three independent intracardiac signal readout channels with pulse-width-modulated outputs. Also, the proposed system is capable of measuring the amplitude and phase of the bioimpedance with pulse-width-modulated outputs for use in rate adaptive...
journal article 2018
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Dezyani, M. (author), Ghafoorifard, Hassan (author), Sheikhaei, Samad (author), Serdijn, W.A. (author)
This paper presents a 60 mV input voltage start-up system for thermoelectric energy harvesting. A new process tolerant inverter cell is proposed, which is functional at supply voltages as low as 60 mV. Using the proposed unit cell, a ring <br/>oscillator has been implemented. The ring oscillator is followed by 40 charge-pump stages, an ultra...
journal article 2018
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