Functional Synthetic Biology

Synthetic biologists have made great progress over the past decade in developing methods for modular assembly of genetic sequences and in engineering biological systems with a wide variety of functions in various contexts and organisms. However, current paradigms in the field entangle sequence and functionality in a manner that makes...

Users and Contemporary SERPs: A (Re-)Investigation: Examining User Interactions and Experiences

The Search Engine Results Page (SERP) has evolved significantly over the last two decades, moving away from the simple ten blue links paradigm to considerably more complex presentations that contain results from multiple verticals and granularities of textual information. Prior works have investigated how user interactions on the SERP are...

Evaluation of rheology and strength development of alkali-activated slag with different silicates sources

This study provides a detailed investigation on the reproducibility of two groups of alkali-activated slag (AAS) mixtures, from both fresh properties and strength development perspectives. Three different commercial sodium silicate solutions and one lab-produced silicate activator (made of silica fume and sodium hydroxide) were used to...

ReproducedPapers.org: Openly Teaching and Structuring Machine Learning Reproducibility

We present ReproducedPapers.org : an open online repository for teaching and structuring machine learning reproducibility. We evaluate doing a reproduction project among students and the added value of an online reproduction repository among AI researchers. We use anonymous self-assessment surveys and obtained 144 responses. Results suggest...

Data Curation for Preclinical and Clinical Multimodal Imaging Studies

Purpose: In biomedical research, imaging modalities help discover pathological mechanisms to develop and evaluate novel diagnostic and theranostic approaches. However, while standards for data storage in the clinical medical imaging field exist, data curation standards for biomedical research are yet to be established. This work aimed at...

A study of the reproducibility of electron beam induced deposition for sub-20 nm lithography

The potential of Electron Beam Induced Deposition (EBID) to become a reliable and reproducible direct-write nanopatterning technique has been investigated. A key requirement is that patterns of sub-20 nm dimension can be reproducibly fabricated and measured. EBID was used for the controlled fabrication of sub-20 nm dense lines on bulk silicon...

Disentangling somatosensory evoked potentials of the fingers: Limitations and clinical potential

In searching for clinical biomarkers of the somatosensory function, we studied reproducibility of somatosensory potentials (SEP) evoked by finger stimulation in healthy subjects. SEPs induced by electrical stimulation and especially after median nerve stimulation is a method widely used in the literature. It is unclear, however, if the EEG...

Reproducibility of the Pleth Variability Index in premature infants

The aim was to assess the reproducibility of the Pleth Variability Index (PVI), developed for non-invasive monitoring of peripheral perfusion, in preterm neonates below 32 weeks of gestational age. Three PVI measurements were consecutively performed in stable, comfortable preterm neonates in the first 48 h of life. On each occasion, pulse...