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Putra, N.E. (author), Leeflang, M.A. (author), Ducret, Verena (author), Patrulea, Viorica (author), Fratila-Apachitei, E.L. (author), Perron, Karl (author), Ye, Hua (author), Zhou, J. (author), Apachitei, I. (author), Zadpoor, A.A. (author)
Implant-associated infections are highly challenging to treat, particularly with the emergence of multidrug-resistant microbials. Effective preventive action is desired to be at the implant site. Surface biofunctionalization of implants through Ag-doping has demonstrated potent antibacterial results. However, it may adversely affect bone...
journal article 2022
document
van Hengel, I.A.J. (author), van Dijk, B. (author), Modaresifar, K. (author), Hooning van Duyvenbode, J. Fred F. (author), Nurmohamed, F. Ruben H.A. (author), Leeflang, M.A. (author), Fluit, A.C. (author), Fratila-Apachitei, E.L. (author), Apachitei, I. (author), Weinans, Harrie (author), Zadpoor, A.A. (author)
Additively manufactured (AM) porous titanium implants may have an increased risk of implant-associated infection (IAI) due to their huge internal surfaces. However, the same surface, when biofunctionalized, can be used to prevent IAI. Here, we used a rat implant infection model to evaluate the biocompatibility and infection prevention...
journal article 2023