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Bisschops, M.A.T. (author), Van der Wielen, L.A. (author), Luyben, K.C.A. (author)Abstract of WO 9733687 (A1) The invention relates to a method and an apparatus for carrying out a treatment in the presence of centrifugal force. The treatment may be a physical or a chemical treatment. For this purpose the first and the second phase are brought into contact with each other. The second phase comprises a phase soluble in the...patent 1997
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Jensen, T.B. (author), Billiet, H.A.H. (author), Van der Wielen, L.A.M. (author)The present invention relates to a method of separating a first solute A and a second solute B using (simulated) moving bed chromatography. According to the present invention at least one of a) a feedstream; and b) a desorbent stream comprises an organic solvent. The use of different solvent liquids for the feedstream and the desorbent stream...patent 2000
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Hofland, G.W. (author), Van der Wielen, L.A. (author), Witkamp, G.J. (author)The invention relates to a method for the preparation of protein agglomerates, by introducing CO2 in an aqueous protein-containing solution. According to the invention CO2 is gradually and while mixing supplied yielding spherical protein agglomerates, after which the pressure is reduced with a rate such that the spherical nature of the protein...patent 2001
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Van Hee, P. (author), Van der Wielen, L.A.M. (author), Van der Lans, R.G.J.M. (author)The invention relates to a method for the production of a fermentation product from an organism cultured in a culture medium, wherein the organism after the formation of the fermentation product is subjected to a lysis treatment in the presence of a lysis-promoting compound. In accordance with the invention, the lysis-promoting agent is a...patent 2005
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Golubovic, M. (author), Ottens, M. (author), Witkamp, G.J. (author), Van der Wielen, L.A. (author)The invention relates to a method of preparing a protein aggregate, wherein an aqueous protein solution is acidified with a pH that lies above the isoelectric point of the protein. In accordance with the invention, a first protein, which through acidificaiton is able to form a protein aggregate, is acidified in the presence of a second protein...patent 2005
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Van der Wielen, L.A.M. (author), Heijnen, J.J. (author)The present invention is directed to a process for the continuous biological production of lipids, hydrocarbons, hydrocarbon like material or mixtures thereof by conversion of a suitable substrate using micro-organisms, in which process the said substrate is continuously, anaerobically fermented to produce lipids, hydrocarbons, hydrocarbon like...patent 2010
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Cuellar Soares, M.C. (author), Van der Wielen, L.A.M. (author), Heeres, A.S. (author)The invention is directed to a method for recovering a lipid or hydrocarbon from a fermentation mixture, comprising the steps of - providing a fermentation mixture wherein the lipid or hydrocarbon is produced by microbial fermentation in a fermentation vessel, which mixture comprises an aqueous phase and a liquid product phase, wherein the...patent 2015