Agent-based mathematical modeling of pancreatic cancer growth and several therapies

Cancer is known as one of the leading causes of death in the world with difficult<br/>diagnose at early stages, poor prognosis and high mortality. Animal-based<br/>experiments and clinical trials have always been the main approach for cancer<br/>research, albeit they may have limitations and ethical issues. Mathematicalmodeling<br/>as an...

Computational modeling of therapy on pancreatic cancer in its early stages

More than eighty percent of pancreatic cancer involves ductal adenocarcinoma with an abundant desmoplastic extracellular matrix surrounding the solid tumor entity. This aberrant tumor microenvironment facilitates a strong resistance of pancreatic cancer to medication. Although various therapeutic strategies have been reported to be effective...