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Bhoopalam, Anirudh Kishore (author), van den Berg, Roy (author), Agatz, Niels (author), Chorus, C.G. (author)Work towards making automated driving systems a reality is well underway. In this study, we look at what is likely to be one of the first widespread implementations of a form of automated driving on public roads, i.e., truck platooning, where virtually connected trucks drive at short headways to save fuel and associated emissions. With...journal article 2023
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Szép, T. (author), van den Berg, T.G.C. (author), Cointe, Nicolas (author), Daniel, Aemiro Melkamu (author), Martinho, Andreia (author), Tang, Tanzhe (author), Chorus, C.G. (author)Social routing schemes are widely regarded as promising tools to reduce traffic congestion in urban networks. We contribute to the growing literature on such schemes and their effect on travel behavior, by exploring the interaction between the characteristics and framing of the scheme on the one hand, and travelers' moral personality and moral...journal article 2023
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Japaridze, A. (author), van Wee, R.G. (author), Gogou, C. (author), Kerssemakers, J.W.J. (author), van den Berg, D.F. (author), Dekker, C. (author)The bacterial chromosome is spatially organized through protein-mediated compaction, supercoiling, and cell-boundary confinement. Structural Maintenance of Chromosomes (SMC) complexes are a major class of chromosome-organizing proteins present throughout all domains of life. Here, we study the role of the Escherichia coli SMC complex MukBEF...journal article 2023
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van den Berg, Cyntha M. (author), Volkov, V. (author), Schnorrenberg, Sebastian (author), Huang, Ziqiang (author), Stecker, Kelly E. (author), Grigoriev, Ilya (author), Gilani, Sania (author), Frikstad, Kari Anne M. (author), Dogterom, A.M. (author)Microtubules are dynamic cytoskeletal polymers, and their organization and stability are tightly regulated by numerous cellular factors. While regulatory proteins controlling the formation of interphase microtubule arrays and mitotic spindles have been extensively studied, the biochemical mechanisms responsible for generating stable...journal article 2023
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Rivera-Arbeláez, José M. (author), Keekstra, Danjel (author), Cofiño-Fabres, Carla (author), Boonen, Tom (author), Dostanic, M. (author), ten Den, Simone A. (author), Vermeul, Kim (author), Mastrangeli, Massimo (author), van den Berg, A (author)The high rate of drug withdrawal from the market due to cardiovascular toxicity or lack of efficacy, the economic burden, and extremely long time before a compound reaches the market, have increased the relevance of human in vitro models like human (patient-derived) pluripotent stem cell (hPSC)-derived engineered heart tissues (EHTs) for the...journal article 2023
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Mahler, M.S. (author), Malone Portu, L.M. (author), van den Berg, D.F. (author), Smith, Leah M. (author), Brouns, S.J.J. (author), Fineran, Peter C. (author)Serratia sp. ATCC 39006 is a Gram-negative bacterium that has been used to study the function of phage defences, such as CRISPR-Cas, and phage counter-defence mechanisms. To expand our phage collection to study the phage-host interaction with Serratia sp. ATCC 39006, we isolated the T4-like myovirus LC53 in Ōtepoti Dunedin, Aotearoa New...journal article 2023
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Hendrikse, H. (author), Hammer, T.C. (author), van den Berg, M.A. (author), Willems, Tom (author), Owen, C.C. (author), van Beek, C. (author), Ebben, Nick J.J. (author), Puolakka, Otto (author), Polojärvi, Arttu (author)Basin tests were performed at the Aalto Ice Tank to gather data on ice-structure action and interaction from ice failing against a vertically sided cylindrical pile. The tests were performed with a real-time hybrid test setup, which combined physical and numerical components to simulate a range of test structures in real-time. The dataset...journal article 2022
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van den Berg, T.G.C. (author), Kroesen, M. (author), Chorus, C.G. (author)Within moral psychology, theories focusing on the conceptualization and empirical measurement of people’s morality in terms of general moral values –such as Moral Foundation Theory- (implicitly) assume general moral values to be relevant concepts for the explanation and prediction of behavior in everyday life. However, a solid theoretical and...journal article 2022
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van den Berg, L. (author), Toja Ortega, S. (author), van Loosdrecht, Mark C.M. (author), de Kreuk, M.K. (author)Aerobic granular sludge (AGS) is an advanced biofilm-based technology for wastewater treatment. Diffusion of substrates into the granules is a key aspect of this technology. Domestic wastewater contains soluble organic substrates of different sizes that could potentially diffuse into the granules. In this study, the relation between the...journal article 2022
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de Bruijn, Douwe S. (author), ten Eikelder, Henricus R.A. (author), Papadimitriou, V. (author), Olthuis, Wouter (author), van den Berg, Albert (author)The assessment of particle and cell size in electrical microfluidic flow cytometers has become common practice. Nevertheless, in flow cytometers with coplanar electrodes accurate determination of particle size is difficult, owing to the inhomogeneous electric field. Pre-defined signal templates and compensation methods have been introduced to...journal article 2022
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van den Berg, M.A. (author), Owen, C.C. (author), Hendrikse, H. (author)This study analyses the results from basin tests with a vertically sided cylindrical pile loaded by ice failing in crushing. Tests were performed with a ‘rigid’ structure and with structural models representing a series of single-degree-of-freedom (SDOF) oscillators covering a wide range of mass, frequency, and damping values. The structural...journal article 2022
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Schoutens, Ken (author), Stoorvogel, Marte (author), van den Berg, M. (author), van den Hoven, Kim (author), Bouma, Tjeerd J. (author), Aarninkhof, S.G.J. (author), Herman, P.M.J. (author), van Loon-Steensma, Jantsje M. (author), Meire, Patrick (author)Nature-based strategies, such as wave attenuation by tidal marshes, are increasingly proposed as a complement to mitigate the risks of failure of engineered flood defense structures such as levees. However, recent analysis of historic coastal storms revealed smaller dike breach dimensions if there were natural, high tidal marshes in front of...journal article 2022
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Berenger-Currias, N.M.L.P. (author), Mircea, Maria (author), Adegeest, Esmée (author), van den Berg, Patrick R. (author), Feliksik, Marleen (author), Hochane, Mazène (author), Idema, T. (author), Tans, S.J. (author), Semrau, Stefan (author)Stem-cell derived in vitro systems, such as organoids or embryoids, hold great potential for modeling in vivo development. Full control over their initial composition, scalability, and easily measurable dynamics make those systems useful for studying specific developmental processes in isolation. Here we report the formation of gastruloids...journal article 2022
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van der Voorn, Tom (author), van den Berg, Caroline (author), Quist, J.N. (author), Kok, Kasper (author)The current COVID-19 pandemic has affected societies across the world while its economic impact has cut deeper than any recession since the Second World War. Climate change is potentially an even more disruptive and complex global challenge. Climate change could cause social and economic damage far larger than that caused by COVID-19. The...journal article 2022
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Kwakernaak, M.C. (author), Koel, Marijn (author), van den Berg, P.M. (author), Kelder, E.M. (author), Jager, W.F. (author)A novel protocol for the synthesis of perylene diimides (PDIs), by reacting perylene dianhydride (PDA) with aliphatic amines is reported. Full conversions were obtained at temperatures between 20 and 60 °C, using DBU as the base in DMF or DMSO. A "green"synthesis of PDIs, that runs at higher temperatures, was developed using K2CO3 in DMSO....journal article 2022
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Wang, Gangqi (author), Heijs, Bram (author), Kostidis, Sarantos (author), Rietjens, Rosalie G.J. (author), Mahfouz, A.M.E.T.A. (author), Chuva de Sousa Lopes, Susana M. (author), van den Berg, Cathelijne W. (author), van den Berg, Bernard M. (author), Rabelink, Ton J. (author)Accumulating evidence demonstrates important roles for metabolism in cell fate determination. However, it is a challenge to assess metabolism at a spatial resolution that acknowledges both heterogeneity and cellular dynamics in its tissue microenvironment. Using a multi-omics platform to study cell-type-specific dynamics in metabolism in...journal article 2022
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Wang, Gangqi (author), Heijs, Bram (author), Kostidis, Sarantos (author), Mahfouz, A.M.E.T.A. (author), Rietjens, Rosalie G.J. (author), Bijkerk, Roel (author), Koudijs, Angela (author), van der Pluijm, Loïs A.K. (author), van den Berg, Cathelijne W. (author)A common drawback of metabolic analyses of complex biological samples is the inability to consider cell-to-cell heterogeneity in the context of an organ or tissue. To overcome this limitation, we present an advanced high-spatial-resolution metabolomics approach using matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI...journal article 2022
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Dekker, W.J.C. (author), Jürgens, H. (author), Ortiz Merino, R.A. (author), Mooiman, C. (author), van den Berg, Remon (author), Kaljouw, Astrid (author), Mans, R. (author), Pronk, J.T. (author)While thermotolerance is an attractive trait for yeasts used in industrial ethanol production, oxygen requirements of known thermotolerant species are incompatible with process requirements. Analysis of oxygen-sufficient and oxygen-limited chemostat cultures of the facultatively fermentative, thermotolerant species Ogataea parapolymorpha...journal article 2022
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van den Berg, S.C. (author), Scharff, R.B.N. (author), Rusak, Z. (author), Wu, J. (author)We present OpenFish: an open source soft robotic fish which is optimized for speed and efficiency. The soft robotic fish uses a combination of an active and passive tail segment to accurately mimic the thunniform swimming mode. Through the implementation of a novel propulsion system that is capable of achieving higher oscillation frequencies...journal article 2022
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van den Berg, L. (author), Pronk, M. (author), van Loosdrecht, Mark C.M. (author), de Kreuk, M.K. (author)Granular sludge processes are frequently used in domestic and industrial wastewater treatment. The granule buoyant density and biomass density are important parameters for the design and operation of granular sludge reactors. Different methods to measure the granule density include the pycnometer method, the Percoll density gradient method,...journal article 2022