Supervised machine learning in microfluidic impedance flow cytometry for improved particle size determination

The assessment of particle and cell size in electrical microfluidic flow cytometers has become common practice. Nevertheless, in flow cytometers with coplanar electrodes accurate determination of particle size is difficult, owing to the inhomogeneous electric field. Pre-defined signal templates and compensation methods have been introduced to...

Automation of the clipping process in cryogenic electron tomography

Cryogenic electron tomography (cryo-ET) is currently the golden standard for imaging cellular tissue at nanometer resolution. The current workflow from cultured cells to final image is however very time-consuming, labor-intensive, expensive, and has a low yield. Moreover, many of the steps in this workflow require practice. Even after practice,...