- document
-
Dekker, Diewertje (author)Accurate short term rain predictions are important for flood early warning systems, emergency services, energy management and other services that that make weather dependent decisions. Recently introduced machine learning models suffer from blurry and unrealistic predictions at longer lead times, causing poor performance on the rarer heavy...master thesis 2022
- document
-
Dekker, M.C. (author)Repetitive Strain Injuries (RSI), also known as Work-Related Upper Limb Disorders (WRULD), surged in the early years of this millennium due to computer work. In this thesis, the magnitude, causes and consequences of this phenomenon for the student population of the Faculty of Industrial Design Engineering (IDE) at the Delft University of...doctoral thesis 2022
- document
-
Dekker, Madelief (author)A guide for the landscape architectural design of an urban forest that helps create realms of experience in order to make people more aware of our connection to nature.<br/><br/>The imbalance between how we live and how the natural world around us works leads to a disconnected relationship with nature. Because of this many people see nature that...master thesis 2022
- document
-
Dekker, Abram (author)Due to the continuously increasing volume of road freight transportation, there is a need to aid or automate truck-trailer driving. Truck docking, the process of parking a truck-trailer combination at a loading dock, is one of the most difficult manoeuvres for professional drivers. In this work, we propose a Model Predictive Control (MPC)-based...master thesis 2022
- document
-
Dekker, Diewertje (author)This additional thesis project is performed as preliminary research for a bigger project that they are going to start at Lund University, to investigate whether the use of a different interpolation methods, to link the precipitation data to the sub-basins centers of the HYPE model, lead to improved model performance. In this report, previously...student report 2022
- document
-
de Haas, K. (author), Berkhout, B (author), Dekker, H.R.E. (author), Broere, W. (author)Determining the scope of (structural) renovation of aging tunnels is a complicated task and modular renovation is becoming increasingly necessary. The COB Tunnel Programme aims at developing the knowledge necessary to renovate these tunnels in a modular fashion, to reduce hindrance as much as possible. Part of this program is the development of...conference paper 2022
- document
-
Janissen, R. (author), Eslami Mossallam, B. (author), Artsimovitch, Irina (author), Depken, S.M. (author), Dekker, N.H. (author)Pausing by bacterial RNA polymerase (RNAp) is vital in the recruitment of regulatory factors, RNA folding, and coupled translation. While backtracking and intra-structural isomerization have been proposed to trigger pausing, our mechanistic understanding of backtrack-associated pauses and catalytic recovery remains incomplete. Using high...journal article 2022
- document
-
Mazur, G.P. (author), van Loo, N. (author), Wang, J. (author), Dvir, T. (author), Wang, Guanzhong (author), Korneychuk, S. (author), Borsoi, F. (author), Dekker, R.C. (author), Badawy, G.H.A. (author), Vinke, Peter (author), Quintero Perez, M. (author), Heedt, S. (author), Kouwenhoven, Leo P. (author)In superconducting quantum circuits, aluminum is one of the most widely used materials. It is currently also the superconductor of choice for the development of topological qubits. However, aluminum-based devices suffer from poor magnetic field compatibility. Herein, this limitation is resolved by showing that adatoms of heavy elements (e.g.,...journal article 2022
- document
-
Fragasso, A. (author), de Vries, Hendrik W. (author), Andersson, John (author), van der Sluis, E.O. (author), van der Giessen, Erik (author), Onck, Patrick R. (author), Dekker, C. (author)Nuclear pore complexes (NPCs) regulate all molecular transport between the nucleus and the cytoplasm in eukaryotic cells. Intrinsically disordered Phe-Gly nucleoporins (FG-Nups) line the central conduit of NPCs to impart a selective barrier where large proteins are excluded unless bound to a transport receptor (karyopherin; Kap). Here, we...journal article 2022
- document
-
Chardon, Florian (author), Japaridze, A. (author), Witt, Hannes (author), Velikovsky, Leonid (author), Chakraborty, Camellia (author), Wilhelm, Therese (author), Dumont, Marie (author), Yang, W.W.W. (author), Dekker, C. (author)Chromosome inheritance depends on centromeres, epigenetically specified regions of chromosomes. While conventional human centromeres are known to be built of long tandem DNA repeats, much of their architecture remains unknown. Using single-molecule techniques such as AFM, nanopores, and optical tweezers, we find that human centromeric DNA...journal article 2022
- document
-
Fayezioghani, A. (author), Dekker, R. (author), Sluys, Lambertus J. (author)Structural components in corrosive environments such as pipelines, bridges, aircrafts, and turbines are imposed to stress corrosion. A stress corrosion model for pit growth should a) accurately consider the electrochemistry of the corrosion process, b) properly deal with the moving interface between solid and electrolyte, and c) effectively...journal article 2022
- document
-
Boskeljon-Horst, Leonie (author), J. de Boer, Robert (author), Sillem, S. (author), Dekker, Sidney W. A. (author)In this study we identify the differences in goal realisation when applying two conflicting paradigms regarding rule perception and management. We gathered more than 30 scenarios where goal conflicts were apparent in a military operational unit. We found that operators repetitively utilized certain routines in executing their tasks in an effort...journal article 2022
- document
-
Fayezioghani, A. (author), Dekker, R. (author), Sluys, Lambertus J. (author)Corrosion is a phenomenon observed in structural components in corrosive environments such as pipelines, bridges, aircrafts, turbines, etc. The computational model of corrosion should enjoy two features: a) accurately considering the electrochemistry of corrosion and b) properly dealing with the moving interface between solid and electrolyte....journal article 2022
- document
-
Dekker, S.W.A. (author), Layson, Mark D. (author), Woods, David D. (author)Following other contributions about the MAX accidents to this journal, this paper explores the role of betrayal and moral injury in safety engineering related to the U.S. federal regulator’s role in approving the Boeing 737MAX—a plane involved in two crashes that together killed 346 people. It discusses the tension between humility and hubris...journal article 2022
- document
-
Kawasaki, S. (author), Yeh, Jia-Jun (author), Saccher, M. (author), Li, Jian (author), Dekker, R. (author)The main limitation of acoustic particle separation for microfluidic application is its low sorting efficiency. This is due to the weak coupling of surface acoustic waves (SAWs) into the microchannel. In this work, we demonstrate bulk acoustic wave (BAW) particle sorting using capacitive micromachined ultrasonic transducers (CMUTs) for the first...conference paper 2022
- document
-
Saccher, M. (author), Lolla, Sai Sandeep (author), Kawasaki, S. (author), Dekker, R. (author)Ultrasound (US) has recently gained attention for powering and communication with implantable devices due to its short wavelength and low attenuation. However, beam mis-alignments cause a sharp decrease in the amount of transferred power and quality of communication. This work investigates a telemetry protocol that relies on the difference in...conference paper 2022
- document
-
Holub, M. (author), Birnie, A.T.F. (author), Japaridze, A. (author), van der Torre, J. (author), Ridder, Maxime den (author), de Ram, C. (author), Pabst, Martin (author), Dekker, C. (author)Chromosome structure and function is studied using various cell-based methods as well as with a range of in vitro single-molecule techniques on short DNA substrates. Here, we present a method to obtain megabase-pair-length deproteinated DNA for in vitro studies. We isolated chromosomes from bacterial cells and enzymatically digested the...journal article 2022
- document
-
Dekker, W.J.C. (author), Jürgens, H. (author), Ortiz Merino, R.A. (author), Mooiman, C. (author), van den Berg, Remon (author), Kaljouw, Astrid (author), Mans, R. (author), Pronk, J.T. (author)While thermotolerance is an attractive trait for yeasts used in industrial ethanol production, oxygen requirements of known thermotolerant species are incompatible with process requirements. Analysis of oxygen-sufficient and oxygen-limited chemostat cultures of the facultatively fermentative, thermotolerant species Ogataea parapolymorpha...journal article 2022
- document
-
Kuijpers, L.C. (author), van Laar, T. (author), Janissen, R. (author), Dekker, N.H. (author)Multiplexed single-molecule magnetic tweezers (MT) have recently been employed to probe the RNA synthesis dynamics of RNA-dependent RNA polymerases (RdRp). Here, we present a protocol for simultaneously probing the RNA synthesis dynamics of hundreds of single polymerases with MT. We describe the preparation of a dsRNA construct for probing...journal article 2022
- document
-
Kim, E. (author), Martin Gonzalez, A. (author), Pradhan, B. (author), van der Torre, J. (author), Dekker, C. (author)Condensin, a structural maintenance of chromosomes (SMC) complex, has been shown to be a molecular motor protein that organizes chromosomes by extruding loops of DNA. In cells, such loop extrusion is challenged by many potential conflicts, for example, the torsional stresses that are generated by other DNA-processing enzymes. It has so far...journal article 2022