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Cohen, Keira A. (author), Manson, Abigail L. (author), Abeel, T.E.P.M.F. (author), Desjardins, Christopher A. (author), Chapman, Sinead B. (author), Hoffner, Sven (author), Birren, Bruce W. (author), Earl, Ashlee M. (author)
Background: While the international spread of multidrug-resistant (MDR) Mycobacterium tuberculosis strains is an acknowledged public health threat, a broad and more comprehensive examination of the global spread of MDR-tuberculosis (TB) using whole-genome sequencing has not yet been performed. Methods: In a global dataset of 5310 M....
journal article 2019
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Manson, Abigail L. (author), Cohen, Keira A (author), Abeel, T.E.P.M.F. (author), Desjardins, Christopher A. (author), Armstrong, Derek T. (author), Barry III, Clifton E. (author), Brand, Jeannette (author), Chapman, Sinéad B. (author), Cho, Sang-Nae (author), Gabrielian, Andrei (author), Salazar, A.N. (author)
Multidrug-resistant tuberculosis (MDR-TB), caused by drug-resistant strains of Mycobacterium tuberculosis, is an increasingly serious problem worldwide. Here we examined a data set of whole-genome sequences from 5,310 M. tuberculosis isolates from five continents. Despite the great diversity of these isolates with respect to geographical...
journal article 2017