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Kenkhuis, Boyd (author), Somarakis, Antonios (author), de Haan, Lorraine (author), Dzyubachyk, Oleh (author), Ijsselsteijn, Marieke E. (author), de Miranda, Noel F. C. C. (author), Lelieveldt, B.P.F. (author), Dijkstra, Jouke (author), Van Roon-Mom, Willeke (author), Höllt, T. (author), van der Weerd, Louise (author)
Brain iron accumulation has been found to accelerate disease progression in amyloid-β(Aβ) positive Alzheimer patients, though the mechanism is still unknown. Microglia have been identified as key players in the disease pathogenesis, and are highly reactive cells responding to aberrations such as increased iron levels. Therefore, using...
journal article 2021