Robust cardiac T1_ρ mapping at 3T using adiabatic spin-lock preparations

Purpose: The aim of this study is to develop and optimize an adiabatic (Formula presented.) ((Formula presented.)) mapping method for robust quantification of spin-lock (SL) relaxation in the myocardium at 3T. Methods: Adiabatic SL (aSL) preparations were optimized for resilience against (Formula presented.) and (Formula presented.)...

Rapid Whole-Knee Quantification of Cartilage Using T ₁, T ₂ ^∗, and T _RAFF2 Mapping With Magnetic Resonance Fingerprinting

Objective: Quantitative Magnetic Resonance Imaging (MRI) holds great promise for the early detection of cartilage deterioration. Here, a Magnetic Resonance Fingerprinting (MRF) framework is proposed for comprehensive and rapid quantification of T ₁, T ₂ ^∗, and T _RAFF2 with whole-knee coverage....

Improving Patient Comfort in MRI with Predictive Acoustic Noise Cancelling

With sound pressure levels reaching up to 130 dB, acoustic noise in Magnetic Resonance Imaging (MRI) is one of the main sources of patient discomfort in otherwise one of the safest medical imaging modalities. In this work, a noise prediction-based approach, termed predictive noise cancelling (PNC), is applied, for the first time, to suppress...

Myocardial Approximate Spin-lock Dispersion Mapping using a Simultaneous T₂ and T_RAFF2 Mapping at 3T MRI

Ischemic heart disease (IHD) is one of the leading causes of death worldwide. Myocardial infarction (MI) represents a third of all IHD cases, and cardiac magnetic resonance imaging (MRI) is often used to assess its damage to myocardial viability. Late gadolinium enhancement (LGE) is the current gold standard, but the use of gadolinium-based...

Adiabatic spin-lock preparations enable robust in vivo cardiac T_1ρ-mapping at 3T

Magnetic Resonance Imaging (MRI) is the clinical gold standard for the assessment of myocardial viability but requires injection of exogenous gadolinium-based contrast agents. Recently, T1ρ-mapping has been proposed as a fully non-invasive alternative for imaging myocardial fibrosis without the need for contrast agent injection. However, its...

High-Resolution Free-Breathing Quantitative First-Pass Perfusion Cardiac MR Using Dual-Echo Dixon With Spatio-Temporal Acceleration

Introduction: To develop and test the feasibility of free-breathing (FB), high-resolution quantitative first-pass perfusion cardiac MR (FPP-CMR) using dual-echo Dixon (FOSTERS; Fat-water separation for mOtion-corrected Spatio-TEmporally accelerated myocardial peRfuSion). Materials and Methods: FOSTERS was performed in FB using a dual...

Retrospective Camera-Based Respiratory Gating in Clinical Whole-Heart 4D Flow MRI

Background: Respiratory gating is generally recommended in 4D flow MRI of the heart to avoid blurring and motion artifacts. Recently, a novel automated contact-less camera-based respiratory motion sensor has been introduced. Purpose: To compare camera-based respiratory gating (CAM) with liver-lung-navigator-based gating (NAV) and no gating ...