Enzyme immobilisation in biocatalysis: Why, what and how

In this tutorial review, an overview of the why, what and how of enzyme immobilisation for use in biocatalysis is presented. The importance of biocatalysis in the context of green and sustainable chemicals manufacture is discussed and the necessity for immobilisation of enzymes as a key enabling technology for practical and commercial viability...

The Application of Nitrile Hydratases in Organic Synthesis

Nitrile hydratases (NHases, E.C. 4.2.1.84) catalyse the transformation of nitriles into the corresponding amides and were first discovered 30 years ago in studies on the microbial degradation of toxic cyano-group-containing compounds. The use of NHases in synthetic chemistry is especially interesting in conversions where the substrate or the...

Utilization of arylaliphatic nitriles by haloalkaliphilic Halomonas nitrilicus sp. nov. isolated from soda soils

An enrichment culture from saline soda soils, using acetate as carbon and energy source and 2- phenylpropionitrile as nitrogen source (PPN) at pH 10, resulted in the isolation of strain ANL-?CH3. The strain was identified as a representative of the genus Halomonas in the Gammaproteobacteria. The bacterium was capable of PPN utilization as a...

Design of a chewing gum that does not fouls the streets and is digestible