Experimental data from ice basin tests with vertically sided cylindrical structures

Basin tests were performed at the Aalto Ice Tank to gather data on ice-structure action and interaction from ice failing against a vertically sided cylindrical pile. The tests were performed with a real-time hybrid test setup, which combined physical and numerical components to simulate a range of test structures in real-time. The dataset...

Classification Of Ice-Induced Vibration Regimes Of Offshore Wind Turbines

Ice-induced vibrations of offshore wind turbines on monopile foundations were investigated experimentally at the Aalto Ice Tank. A real-time hybrid test setup was developed allowing to accurately simulate the motion of a wind turbine in interaction with ice, incorporating the multi-modal aspects of the interaction and the effect of simultaneous...

Experimental study on ice-structure interaction phenomena of vertically sided structures

This study analyses the results from basin tests with a vertically sided cylindrical pile loaded by ice failing in crushing. Tests were performed with a ‘rigid’ structure and with structural models representing a series of single-degree-of-freedom (SDOF) oscillators covering a wide range of mass, frequency, and damping values. The structural...

Ice Basin Tests For Ice-Induced Vibrations Of Offshore Structures In The Shiver Project

With the recent surge in development of offshore wind in the Baltic Sea, Bohai Sea and other ice-prone regions, a need has arisen for new basin tests to qualify the interaction between offshore wind turbines and sea ice. To this end, a series of model tests was performed at the Aalto ice basin as part of the SHIVER project. The tests were aimed...

Impact of Velvet Complex on Transcriptome and Penicillin G Production in Glucose-Limited Chemostat Cultures of a ?-Lactam High-Producing Penicillium chrysogenum Strain

The multicomponent global regulator Velvet complex has been identified as a key regulator of secondary metabolite production in Aspergillus and Penicillium species. Previous work indicated a massive impact of PcvelA and PclaeA deletions on penicillin production in prolonged batch cultures of P. chrysogenum, as well as substantial changes in...

Metabolic engineering of ?-oxidation in Penicillium chrysogenum for improved semi-synthetic cephalosporin biosynthesis

Industrial production of semi-synthetic cephalosporins by Penicillium chrysogenum requires supplementation of the growth media with the side-chain precursor adipic acid. In glucose-limited chemostat cultures of P. chrysogenum, up to 88% of the consumed adipic acid was not recovered in cephalosporin-related products, but used as an additional...

Intermediate frequency band digitized high dynamic range radiometer system for plasma diagnostics and real-time Tokamak control

An intermediate frequency (IF) band digitizing radiometer system in the 100–200 GHz frequency range has been developed for Tokamak diagnostics and control, and other fields of research which require a high flexibility in frequency resolution combined with a large bandwidth and the retrieval of the full wave information of the mm-wave signals...

Exploring and dissecting genome-wide gene expression responses of Penicillium chrysogenum to phenylacetic acid consumption and penicillinG production

OA Fund TU Delft Background Since the discovery of the antibacterial activity of penicillin by Fleming 80 years ago, improvements of penicillin titer were essentially achieved by classical strain improvement through mutagenesis and screening. The recent sequencing of Penicillium chrysogenum strain Wisconsin1255-54 and the availability of...

Function and regulation of acetyl-coenzyme A synthetase in the yeast Saccharomyces cerevisiae

The Two Acetyl-coenzyme A Synthetases of Saccharomyces cerevisiae Differ with Respect to Kinetic Properties and Transcriptional Regulation