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Luttik, M.A.H. (author), Vuralhan, Z (author), Suir, E (author), Braus, G.H. (author), Pronk, J.T. (author), Daran, J.G. (author)A quantitative analysis of the impact of feedback inhibition on aromatic amino acid biosynthesis was performed in chemostat cultures of Saccharomyces cerevisiae. Introduction of a tyrosine-insensitive allele of ARO4 (encoding 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase) caused a three-fold increase of intracellular phenylalanine and...journal article 2008
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Vuralhan, Z. (author)Saccharomyces cerevisiae is a popular industrial microorganism. It has since long been used in bread, beer and wine making. More recently it is also being applied for heterologous protein production and as a target organism for metabolic engineering. The work presented in this thesis describes how S. cerevisiae may be used as a metabolic...doctoral thesis 2006
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- Vuralhan, Z. (author), Luttik, M.A. (author), Tai, S.L. (author), Boer, V.M. (author), Morais, M.A. (author), Schipper, D. (author), Almering, M.J. (author), Kotter, P. (author), Dickinson, J.R. (author), Daran, J.M. (author), Pronk, J.T. (author) journal article 2005
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- Vuralhan, Z. (author), Morais, M.A. (author), Tai, S.L. (author), Piper, M.D. (author), Pronk, J.T. (author) journal article 2003