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Penkin, D. (author), Janssen, G.J.M. (author), Yarovoy, A. (author)To effectively localise a source node in a dense wireless tiny-sensor network with an arbitrary 2D/3D node distribution, a novel approach suitable to describe the hop progress of source-to-sink path in such a system is proposed. In this approach, the network topology is described as a regular lattice and relates the statistical parameters of the...journal article 2014
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Lobo-Prat, J. (author), Keemink, A.Q.L. (author), Stienen, A.H.A. (author), Schouten, A.C. (author), Veltink, P.H. (author), Koopman, B.F.J.M. (author)Background: The performance capabilities and limitations of control interfaces for the operation of active movement-assistive devices remain unclear. Selecting an optimal interface for an application requires a thorough understanding of the performance of multiple control interfaces. Methods: In this study the performance of EMG-, force- and...journal article 2014
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Skupien, E. (author), Berger, R.J. (author), Santos, V.P. (author), Gascon, J. (author), Makkee, M. (author), Kreutzer, M.T. (author), Kooyman, P.J. (author), Moulijn, J.A. (author), Kapteijn, F. (author)Benzyl alcohol oxidation was carried out in toluene as solvent, in the presence of the potentially inhibiting oxidation products benzaldehyde and benzoic acid. Benzoic acid, or a product of benzoic acid, is identified to be the inhibiting species. The presence of a basic potassium salt (K2CO3 or KF) suppresses this inhibition, but promotes the...journal article 2014
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Junicke, H. (author), Abbas, B. (author), Oentoro, J. (author), Van Loosdrecht, M. (author), Kleerebezem, R. (author)Identification of individual biomass concentrations is a crucial step towards an improved understanding of anaerobic digestion processes and mixed microbial conversions in general. The knowledge of individual biomass concentrations allows for the calculation of biomass specific conversion rates which form the basis of anaerobic digestion models....journal article 2014
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De Jong, J. (author), Akhtar, W. (author), Badhai, J. (author), Rust, A.G. (author), Rad, R. (author), Hilkens, J. (author), Berns, A. (author), Van Lohuizen, M. (author), Wessels, L.F.A. (author), De Ridder, J. (author)The ability of retroviruses and transposons to insert their genetic material into host DNA makes them widely used tools in molecular biology, cancer research and gene therapy. However, these systems have biases that may strongly affect research outcomes. To address this issue, we generated very large datasets consisting of to unselected...journal article 2014
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Fleerkotte, B.M. (author), Koopman, B. (author), Buurke, J.H. (author), Van Asseldonk, E.H.F. (author), Van der Kooij, H. (author), Rietman, J.S. (author)Background There is increasing interest in the use of robotic gait-training devices in walking rehabilitation of incomplete spinal cord injured (iSCI) individuals. These devices provide promising opportunities to increase the intensity of training and reduce physical demands on therapists. Despite these potential benefits, robotic gait-training...journal article 2014
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Van den Berg, B.A. (author), Reinders, M.J. (author), Roubos, J.A. (author), De Ridder, D. (author)Background Amino acid sequences and features extracted from such sequences have been used to predict many protein properties, such as subcellular localization or solubility, using classifier algorithms. Although software tools are available for both feature extraction and classifier construction, their application is not straightforward,...journal article 2014
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Resch, V.A. (author), Jin, J. (author), Chen, B.S. (author), Hanefeld, U. (author)The Michael hydratase – alcohol dehydrogenase (MhyADH) from Alicycliphilus denitrificans was previously identified as a bi-functional enzyme performing a hydration of ?,?-unsaturated ketones and subsequent oxidation of the formed alcohols. The investigations of the bi-functionality were based on a spectrophotometric assay and an activity...journal article 2014
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Nillesen, A.L. (author)This paper describes an integral approach to flood-risk protection and spatial design that allows for an active involvement of landscape architects and urban designers in the allocation of flood-risk interventions within the Dutch Delta. The Dutch Rijnmond–Drechtsteden area is used as a case study to demonstrate how choices regarding the scale...journal article 2014
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Ding, J. (author), Van der A, R.J. (author), Mijling, B. (author), Levelt, P.F. (author), Hao, N. (author)The Nanjing Government has taken temporary environmental regulations to guarantee good air quality during the Youth Olympic Games (YOG) in 2014. We study the effect of those regulations by applying the emission estimate algorithm DECSO (Daily Emission estimates Constrained by Satellite Observations) to measurements of the Ozone Monitoring...journal article 2014
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Pande, S. (author), Arkesteijn, L. (author), Savenije, H.H.G. (author), Bastidas, L.A. (author)This paper presents evidence that model prediction uncertainty does not necessarily rise with parameter dimensionality (the number of parameters). Here by prediction we mean future simulation of a variable of interest conditioned on certain future values of input variables. We utilize a relationship between prediction uncertainty, sample size...journal article 2014
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Mata Pavia, J. (author), Wolf, M. (author), Charbon, E. (author)Single-photon avalanche diode (SPAD) imagers typically have a relatively low fil factor, i.e. a low proportion of the pixel’s surface is light sensitive, due to in-pixel circuitry. We present a microlens array fabricated on a 128x128 single-photon avalanche diode (SPAD) imager to enhance its sensitivity. The benefit and limitations of these...journal article 2014
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Duintjer Tebbens, R.J. (author), Kalkowska, D.A. (author), Wassilak, S.G.F. (author), Pallansch, M.A. (author), Cochi, S.L. (author), Thompson, K.M. (author)Background Global efforts to eradicate wild polioviruses (WPVs) continue to face challenges due to uninterrupted endemic WPV transmission in three countries and importation-related outbreaks into previously polio-free countries. We explore the potential role of including older children and adults in supplemental immunization activities (SIAs) to...journal article 2014
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Siebelt, M. (author), Groen, H.C. (author), Koelewijn, S.J. (author), De Blois, E. (author), Sandker, M. (author), Waarsing, J.H. (author), Müller, C. (author), Van Osch, G.J.V.M. (author), De Jong, M. (author), Weinans, H.H. (author)Introduction Articular cartilage needs sulfated-glycosaminoglycans (sGAGs) to withstand high pressures while mechanically loaded. Chondrocyte sGAG synthesis is regulated by exposure to compressive forces. Moderate physical exercise is known to improve cartilage sGAG content and might protect against osteoarthritis (OA). This study investigated...journal article 2014
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Yakaboylu, O. (author), Harinck, J. (author), Smit, K.G. (author), De Jong, W. (author)The supercritical water gasification process is an alternative to both conventional gasification as well as anaerobic digestion as it does not require drying and the process takes place at much shorter residence times; a few minutes at most. The drastic changes in the thermo-physical properties of water from the liquid state to the supercritical...journal article 2014
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Savenije, H.H.G. (author), Hoekstra, A.Y. (author), Van der Zaag, P. (author)This paper reviews the changing relation between human beings and water since the Industrial Revolution, a period that has been called the Anthropocene because of the unprecedented scale at which humans have altered the planet during this time. We show how the rapidly changing world urges us to continuously improve our understanding of the...journal article 2014
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Cai, H. (author), Savenije, H.H.G. (author), Toffolon, M. (author)The effect of river discharge on tidal damping in estuaries is explored within one consistent theoretical framework where analytical solutions are obtained by solving four implicit equations, i.e. the phase lag, the scaling, the damping and the celerity equation. In this approach the damping equation is obtained by subtracting the envelope...journal article 2014
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Farahmand, S. (author), Giannakis, G.B. (author), Leus, G.J.T. (author), Tian, Z. (author)Multi-target tracking is mainly challenged by the nonlinearity present in the measurement equation and the difficulty in fast and accurate data association. To overcome these challenges, the present paper introduces a grid-based model in which the state captures target signal strengths on a known spatial grid (TSSG). This model leads to linear...journal article 2014
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Deibel, E. (author)The introduction of open source in the life sciences is increasingly being suggested as an alternative to patenting. This is an alternative, however, that takes its shape at the intersection of the life sciences and informatics. Numerous examples can be identified wherein open source in the life sciences refers to access, sharing and...journal article 2014
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Van Wijk, A.J.M. (author), Verhoef, L. (author)Fuel cell cars can provide more efficient and cleaner transportation. However, we use our cars for transportation only 5% of the time. When parked, the fuel cell in the car can produce electricity from hydrogen, which is cleaner and more efficient than the current electricity system, generating useful ‘waste’ products in the form of heat and...book 2014