The Development of a Cartilage Specific Bioink for Three-Dimensional Bioprinting

Bioprinting is a promising technique that has the ability to generate complex tissue structures for articular cartilage (AC) repair and regeneration. However, most biomaterials used for bioprinting are incapable of representing the complexity of native extracellular matrix (ECM). In this study, a novel cartilage specific bioink has been...

4D Bioprinting: Temporal Stiffening of Mesenchymal Stem Cell-Laden Hyaluronic Acid-Alginate Scaffolds for Cartilage Constructs

Three-dimensional (3D) bioprinting studies the initial condition of printed constructs, which makes construct static, and neglects the dynamic changes in natural tissue conformation during tissue repair, disease progression and regeneration processes. Therefore, the concept of four-dimensional (4D) bioprinting has been introduced that allows for...