Searched for: department%3A%22ImPhys%255C%257Eslsh%257EImaging%255C+Physics%22
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Weppelman, I.G.C. (author), Moerland, R.J. (author), Zhang, L (author), Kieft, E. (author), Kruit, P. (author), Hoogenboom, J.P. (author)
Crucial for the field of ultrafast electron microscopy is the creation of sub-picosecond, high brightness electron pulses. The use of a blanker to chop the beam that originates from a high brightness Schottky source may provide an attractive alternative to direct pulsed laser illumination of the source. We have recently presented the concept...
journal article 2019
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Kragt, Augustinus J.J. (author), Hoekstra, Davey C. (author), Stallinga, S. (author), Broer, Dirk J. (author), Schenning, Albertus P.H.J. (author)
Engineering the helical structure of chiral photonic materials in three dimensions remains a challenge. 3D helix engineered photonic materials are fabricated by local stratification in a photopolymerizable chiral nematic liquid crystal. The obtained chiral photonic materials reflect both handedness of circular polarized light and show super...
journal article 2019
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Jahangir, S. (author), Wagner, E.C. (author), Mudde, R.F. (author), Poelma, C. (author)
Cavitation is a complicated multiphase phenomenon, where the production of vapor cavities leads to an opaque flow. Exploring the internal structures of the cavitating flows is one of the most significant challenges in this field of study. While it is not possible to visualize the interior of the cavity with visible light, we use X-ray...
journal article 2019
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Man, Z. (author), Dou, X. (author), Fu, Shenggui (author)
We show that elongating a tightly focused field in the direction perpendicular to the optical axis is possible. We demonstrate our approach by specially shaping the Pancharatnam–Berry (PB) phase. Moreover, the analytical formulae required to calculate the strength vectors and energy flux of the three-dimensional electromagnetic fields near...
journal article 2019
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Zonneveld, Hazel I. (author), Pruim, R.H.R. (author), Bos, Daniel (author), Vrooman, Henri A. (author), Muetzel, Ryan L. (author), Hofman, Albert (author), Rombouts, Serge ARB (author), van der Lugt, Aad (author), Niessen, W.J. (author)
Structural brain markers are studied extensively in the field of neurodegeneration, but are thought to occur rather late in the process. Functional measures such as functional connectivity are gaining interest as potentially more subtle markers of neurodegeneration. However, brain structure and function are also affected by ‘normal’ brain...
journal article 2019
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van der Graaff, L. (author), Stallinga, S. (author)
Confocal fluorescent imaging is the de facto standard modality for fluorescence imaging. However, the point-to-point scanning technique leads to a very limited throughput and makes the technique unsuitable for large area and fast multi-focal scanning. We propose an architecture for highly efficient 3D line confocal fluorescence imaging. Our...
conference paper 2019
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Hesam Mahmoudi Nezhad, N. (author), Ghaffarian Niasar, M. (author), Mohammadi Gheidari, A. (author), Hagen, C.W. (author), Kruit, P. (author)
In electrostatic charged particle lens design, optimization of a multi-electrode lens with many free optimization parameters is still quite a challenge. A fully automated optimization routine is not yet available, mainly because the lens potential calculations are often done with very time-consuming methods that require meshing of the lens...
journal article 2019
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van der Graaff, L. (author), van Leenders, Geert J. L. H. (author), Boyaval, Fanny (author), Stallinga, S. (author)
Confocal scanning microscopy is the de facto standard modality for fluorescence imaging. Point scanning, however, leads to a limited throughput and makes the technique unsuitable for fast multi-focal scanning over large areas. We propose an architecture for multi-focal fluorescence imaging that is scalable to large area imaging. The design is...
journal article 2019
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Siemons, M.E. (author), Hulleman, C.N. (author), Thorsen, R.Ø. (author), Smith, C.S. (author), Stallinga, S. (author)
Point spread function (PSF) engineering is used in single emitter localization to measure the emitter position in 3D and possibly other parameters such as the emission color or dipole orientation as well. Advanced PSF models such as spline fits to experimental PSFs or the vectorial PSF model can be used in the corresponding localization...
journal article 2018
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Thorsen, R.Ø. (author), Hulleman, C.N. (author), Mathias, Hammer (author), Grunwald, David (author), Stallinga, S. (author), Rieger, B. (author)
Recently, Franke, Sauer and van de Linde introduced a way to estimate the axial position of single-molecules (TRABI). To this end, they compared the detected photon count from a temporal radial-aperture-based intensity estimation to the estimated count from Gaussian point-spread function (PSF) fitting to the data. Empirically they found this...
working paper 2018
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Hulleman, C.N. (author), Huisman, Maximiliaan (author), Moerland, R.J. (author), Gruenwald, David (author), Stallinga, S. (author), Rieger, B. (author)
Light microscopy, allowing sub-diffraction-limited resolution, has been among the fastest developing techniques at the interface of biology, chemistry, and physics. Intriguingly no theoretical limit exists on how far the underlying measurement uncertainty can be lowered. In particular data fusion of large amounts of images can reduce the...
journal article 2018
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Hulleman, C.N. (author), Huisman, Maximiliaan (author), Moerland, R.J. (author), Grünwald, David (author), Stallinga, S. (author), Rieger, B. (author)
In article number 1700323, a sparsity‐inducing scheme based on widefield stimulated emission depletion, which requires stringent control of the polarization state of both the excitation and depletion laser, is introduced by Bernd Rieger and co‐workers for superresolution fluorescence microscopy. The ideal state involves excitation and depletion...
journal article 2018
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Berlich, Ren (author), Stallinga, S. (author)
An approach for designing purely refractive optical elements that generate engineered, multi-order-helix point spread functions (PSFs) with large peak separation for passive, optical depth measurement is presented. The influence of aberrations on the PSF’s rotation angle, which limits the depth retrieval accuracy, is studied numerically and...
journal article 2018
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Chaker, Layal (author), Cremers, Lotte G M (author), Korevaar, Tim I.M. (author), De Groot, Marius (author), Dehghan, Abbas (author), Franco, Oscar H. (author), Niessen, W.J. (author), Ikram, M. Arfan (author), Peeters, Robin P. (author), Vernooij, Meike W. (author)
Thyroid hormone (TH) is crucial during neurodevelopment, but high levels of TH have been linked to neurodegenerative disorders. No data on the association of thyroid function with brain imaging in the general population are available. We therefore investigated the association of thyroid-stimulating hormone and free thyroxine (FT4) with...
journal article 2018
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Langen, Carolyn D. (author), Muetzel, Ryan (author), Blanken, Laura (author), van der Lugt, Aad (author), Tiemeier, Henning (author), Verhulst, F.A.H. (author), Niessen, W.J. (author), White, Tonya (author)
Introduction: Typical brain development is characterized by specific patterns of maturation of functional networks. Cortico-cortical connectivity generally increases, whereas subcortico-cortical connections often decrease. Little is known about connectivity changes amongst different subcortical regions in typical development. Methods: This...
journal article 2018
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Schillinger, F. (author), Schildhauer, TJ (author), Maurer, S. (author), Wagner, E.C. (author), Mudde, R.F. (author), van Ommen, J.R. (author)
The performance of fluidized bed reactors strongly depends on the bubble behavior, for which reason knowledge concerning the bubble properties is important for modeling and reactor optimization. X-ray measurements can be used to characterize bubbles within the cross-section of a fluidized bed on a laboratory scale, but cannot easily be...
journal article 2018
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Thorsen, R.Ø. (author), Hulleman, C.N. (author), Hammer, Mathias (author), Grünwald, David (author), Stallinga, S. (author), Rieger, B. (author)
journal article 2018
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Haringa, C. (author), Mudde, R.F. (author), Noorman, H.J. (author)
Euler–Lagrange computational fluid dynamics simulations offer great potential for the integration of transport dynamics and metabolic dynamics in fermentation systems. Since the seminal work of Lapin et al. [1,2], progress has been made, mainly in the analysis of CFD data and translation to laboratory setup designs. Different large-scale...
journal article 2018
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van der Graaff, L. (author), Boyaval, Fanny (author), van Vliet, L.J. (author), Stallinga, S. (author)
In the field of pathology there is an ongoing transition to the use of Whole Slide Imaging (WSI) systems which scan tissue slides at intermediate resolution (0∼.25 μm) and high throughput (15mm<sup>2</sup>=min) to digital image files. Most scanners currently on the market are line-sensor based push-broom scanners for three-color (RGB)...
conference paper 2018
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Heydarian, H. (author), Schueder, Florian (author), Strauss, Maximilian T. (author), van Werkhoven, Ben (author), Fazel, Mohamadreza (author), Lidke, K.A. (author), Jungmann, Ralf (author), Stallinga, S. (author), Rieger, B. (author)
Methods that fuse multiple localization microscopy images of a single structure can improve signal-to-noise ratio and resolution, but they generally suffer from template bias or sensitivity to registration errors. We present a template-free particle-fusion approach based on an all-to-all registration that provides robustness against...
journal article 2018
Searched for: department%3A%22ImPhys%255C%257Eslsh%257EImaging%255C+Physics%22
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