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Dawes, G.J.S. (author), Fratila-Apachitei, L.E. (author), Necula, B.S. (author), Apachitei, I. (author), Witkamp, G.J. (author), Duszczyk, J. (author)
The aim of the present study was to investigate the morphology and function of a drug eluting metallic porous surface produced by the immobilization of poly lactide-co-glycolide microspheres bearing dexamethasone onto plasma electrolytically oxidized Ti–6Al–7Nb medical alloy. Spheres of 20 µm diameter were produced by an oilin-water emulsion...
journal article 2009
document
Dawes, G.J.S. (author), Fratila-Apachitei, L.E. (author), Mulia, K. (author), Apachitei, I. (author), Witkamp, G.J. (author), Duszczyk, J. (author)
Drug delivery systems (DDS) based on poly (lactide-co-glycolide) (PLGA) microspheres and nanospheres have been separately studied in previous works as a means of delivering bioactive compounds over an extended period of time. In the present study, two DDS having different sizes of the PLGA spheres were compared in morphology, drug (dexamethasone...
journal article 2009