Yen, J. (author), White, R.M. (author), Wedge, D.C. (author), Van Loo, P. (author), De Ridder, J. (author), Capper, A. (author), Richardson, J. (author), Jones, D. (author), Raine, K. (author), Watson, I.R. (author) Melanoma is the most deadly form of skin cancer. Expression of oncogenic BRAF or NRAS, which are frequently mutated in human melanomas, promote the formation of nevi but are not sufficient for tumorigenesis. Even with germline mutated p53, these engineered melanomas present with variable onset and pathology, implicating additional somatic...
journal article 2013
