Heart-on-chip: functional lipoprotein lipase (LPL) expression in co-cultures of cardiomyocytes and endothelial cells

Introduction | Cardiovascular diseases (CVD) are the number one cause of death worldwide. Individuals with a high risk of developing CVD are nowadays mainly treated with cholesterol lowering drugs. Although disease risk can be lowered by a maximum of 40% in this way, a significant untreatable residual risk is left. Therefore, there is a big...