Optimisation-based wavefront sensorless adaptive optics for microscopy

Microscopy is an essential tool for life sciences. Thanks to the development of confocal and multiphoton microscopy, scientists are able to obtain high-resolution 3D views of biological specimens. Nevertheless, spatial variations in the index of refraction within specimens cause aberrations that degrade the quality of the 3D views. One can...

Optimization-based wavefront sensorless adaptive optics for multiphoton microscopy

Optical aberrations have detrimental effects in multiphoton microscopy. These effects can be curtailed by implementing model-based wavefront sensorless adaptive optics, which only requires the addition of a wavefront shaping device, such as a deformable mirror (DM) to an existing microscope. The aberration correction is achieved by maximizing a...

Systematic comparison of the use of annular and Zernike circle polynomials for annular wavefronts

The theory of wavefront analysis of a noncircular wavefront is given and applied for a systematic comparison of the use of annular and Zernike circle polynomials for the analysis of an annular wavefront. It is shown that, unlike the annular coefficients, the circle coefficients generally change as the number of polynomials used in the expansion...

Fast reconstruction and prediction of frozen flow turbulence based on structured Kalman filtering

Efficient and optimal prediction of frozen flow turbulence using the complete observation history of the wavefront sensor is an important issue in adaptive optics for large ground-based telescopes. At least for the sake of error budgeting and algorithm performance, the evaluation of an accurate estimate of the optimal performance of a particular...

Liquid-crystal intraocular adaptive lens with wireless control

We present a prototype of an adaptive intraocular lens based on a modal liquid-crystal spatial phase modulator with wireless control. The modal corrector consists of a nematic liquid-crystal layer sandwiched between two glass substrates with transparent low- and high-ohmic electrodes, respectively. Adaptive correction of ocular aberrations is...