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Bozic, M. (author), Rapacchi, Stanislas (author), Tao, Q. (author), Pierce, Iain (author), Thornton, George (author), Nitsche, Christian (author), Treibel, Thomas A. (author), Schad, Lothar R. (author), Weingärtner, S.D. (author)Purpose: To investigate and mitigate the influence of physiological and acquisition-related parameters on myocardial blood flow (MBF) measurements obtained with myocardial Arterial Spin Labeling (myoASL). Methods: A Flow-sensitive Alternating Inversion Recovery (FAIR) myoASL sequence with bSSFP and spoiled GRE (spGRE) readout is investigated...journal article 2023
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Bladt, Piet (author), den Dekker, A.J. (author), Clement, Patricia (author), Achten, Eric (author), Sijbers, Jan (author)Multi-post-labeling-delay pseudo-continuous arterial spin labeling (multi-PLD PCASL) allows for absolute quantification of the cerebral blood flow (CBF) as well as the arterial transit time (ATT). Estimating these perfusion parameters from multi-PLD PCASL data is a non-linear inverse problem, which is commonly tackled by fitting the single...journal article 2019
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Leeuwis, Anna E. (author), Hooghiemstra, Astrid M. (author), Amier, Raquel (author), Ferro, Doeschka A. (author), Franken, Leonie (author), Nijveldt, Robin (author), Kuijer, Joost P A (author), Bronzwaer, Anne Sophie G T (author), van Lieshout, Johannes J. (author), Rietberg, Marc B. (author), Veerbeek, Janne M. (author), Huijsmans, Rosalie J. (author), Backx, Frank J G (author), Teunissen, Charlotte E. (author), Bron, Esther E. (author), Barkhof, Frederik (author), Prins, Niels D. (author), Shahzad, Rahil (author), Niessen, W.J. (author), de Roos, Albert (author), van Osch, Matthias J P (author), van Rossum, Albert C. (author), Biessels, Geert J. (author), van der Flier, Wiesje M. (author)There is evidence for a beneficial effect of aerobic exercise on cognition, but underlying mechanisms are unclear. In this study, we test the hypothesis that aerobic exercise increases cerebral blood flow (CBF) in patients with vascular cognitive impairment (VCI). This study is a multicenter single-blind randomized controlled trial among 80...journal article 2017