IAmHOME: Transforming an existing house into a smart house to provide for the well-being of its residents

This thesis investigates the transition of traditional houses into Smart Homes, emphasizing the improvement of residents’ well-being, particularly for those aged 50 to 60. It is set against the rapid growth of Smart Home Devices enabled by the Internet of Things, facilitating easy control and monitoring of home features. There has been a...

Configurations of the SARS-CoV-2 nucleocapsid protein: A molecular dynamics approach to understanding its role in genome packaging

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory virus capable of infecting humans and causing mild to severe complications during and after infection, which collectively comprise coronavirus disease 2019 (COVID-19). After an initial local epidemic in late 2019, the virus quickly spread on a global scale and was...

Exploring the Correlation Between Functional Gradients in Material Properties and Solute Diffusion Across the Osteochondral Interface

The solute transport across the osteochondral (OC) interface is of crucial metabolic importance for a normal function of articular cartilage, and, therefore, for the OC interface as a whole. A better understanding how the mechanical- and physiological properties of the OC interface affect the solute transport across the OC interface could lead...

Computational Modelling of the Role of Leadership Style for Its Context-Sensitive Control Over Multilevel Organisational Learning

This paper addresses formalisation and computational modelling of context-sensitive control over multilevel organisational learning and in particular the role of the leadership style in influencing feed forward learning flows. It addresses a realistic case study with focus on the role of managers for control of multilevel organisational learning...

Molten Metal Oscillatory Behaviour in Advanced Fusion-based Manufacturing Processes

The growing demand for manufactured products with complex geometries requiring advanced fusion-based manufacturing techniques emphasises the importance of process development and optimisation to reduce the risk of adverse outcomes, which is currently impeded with traditional approaches (trial and error experiments). Development, optimisation and...

Experimental analysis and simulation of low-velocity impact damage of composite laminates

The capability to accurately analyse the response of multi-directional composite laminates during impact events is of high importance for the design of lightweight aircraft structures. In this work, both experimental and numerical analyses are performed covering a large design-space of laminates for all aspects from on-set of damage and...

Modelling Human Word Learning and Recognition Using Visually Grounded Speech

Many computational models of speech recognition assume that the set of target words is already given. This implies that these models learn to recognise speech in a biologically unrealistic manner, i.e. with prior lexical knowledge and explicit supervision. In contrast, visually grounded speech models learn to recognise speech without prior...

Effect of different femur shapes on the development of cam-type deformities: The development of a combined bone growth and remodeling algorithm to investigate the effect of different femur shapes generated by a SSAM on the development of cam-type deformities

Introduction: A combined bone growth and remodeling model should be created, to investigate the effect of different femur shapes on the risk of developing cam type deformities. The different femur shapes needed for this study can be created using a statistical shape and appearance model (SSAM). The workflow of the combined bone growth and...

A 3D separable cohesive element for modelling the coupled failure in laminated composite materials

The interaction between matrix cracks and interface delamination is a major failure mechanism in composite laminates and has been a subject of active research in recent years. Although coupled failure behaviour of composite laminates between matrix cracks and delamination has been observed in experiments, accurate modelling of this phenomenon...

Design of an Integral Propulsion System Analysis Tool (IPSAT): The Design and Construction of a Modular Propulsion System Design Tool

The Nature and Catalytic Function of Cation Sites in Zeolites: a Computational Perspective

Zeolites have a broad spectrum of applications as robust microporous catalysts for various chemical transformations. The reactivity of zeolite catalysts can be tailored by introducing heteroatoms either into the framework or at the extraframework positions that gives rise to the formation of versatile Brønsted acid, Lewis acid and redox...