Dual-contrast computed tomography enables detection of equine posttraumatic osteoarthritis in vitro

To prevent the progression of posttraumatic osteoarthritis, assessment of cartilage composition is critical for effective treatment planning. Posttraumatic changes include proteoglycan (PG) loss and elevated water content. Quantitative dual-energy computed tomography (QDECT) provides a means to diagnose these changes. Here, we determine the...

Effect of Bath Condition on the Diffusion of Contrast Agents Across Articular Cartilage

In the present study, the effect of concentration, osmolality and charge of x-ray contrast agents on their diffusion and equilibrium distribution across different zones of cartilage was investigated. Full-thickness cartilage discs (Ø = 8.5 mm, n = 3) were extracted from healthy equine femoral condyle (n = 2). The diffusion of four different...