Bone biopsy devices - a patent review

Introduction: Bone biopsies have great value for the diagnosis of, amongst others, hematologic diseases. Although the bone biopsy procedure is mostly performed minimally invasive with the use of a slender cannula, the patient may still experience discomfort, especially when the procedure has to be repeated due to an unsuccessful biopsy. Areas...

Beyond the pedicle screw–a patent review

Purpose: This review provides an overview of the patent literature on posteriorly placed intrapedicular bone anchors. Conventional pedicle screws are the gold standard to create a fixation in the vertebra for spinal fusion surgery but may lack fixation strength, especially in osteoporotic bone. The ageing population demands new bone anchors...

Focal therapy for localized cancer: a patent review

Introduction: Conventional cancer treatments such as radical surgery and systemic therapy targeting the organ or organ system might have side effects because of damage to the surrounding tissue. For this reason, there is a need for new instruments that focally treat cancer. Areas covered: This review provides a comprehensive overview of the...

Design of non-assembly mechanisms: A state-of-the-art review

Additive Manufacturing (AM) or 3D printing has enabled the production of increasingly complex parts that are difficult to produce with conventional manufacturing methods. Its additive nature has made it possible to create interlocking parts in a single production step. This creates opportunities for new ways of designing and producing...

Needle-like instruments for steering through solid organs: A review of the scientific and patent literature

High accuracy and precision in reaching target locations inside the human body is necessary for the success of percutaneous procedures, such as tissue sample removal (biopsy), brachytherapy, and localized drug delivery. Flexible steerable needles may allow the surgeon to reach targets deep inside solid organs while avoiding sensitive structures ...