An interface-enriched generalized finite element method for the analysis and topology optimization of 2-D electromagnetic problems

The computational analysis of nanophotonic devices is usually carried out via the standard finite element method (FEM). However, FEM requires meshes that are fitted to the devices’ boundaries, so making changes to the geometry (and thus the mesh) results in an inefficient process at best. Such an approach is therefore at odds when conducting...

3D printed patient-specific fixation plates for the treatment of slipped capital femoral epiphysis: Topology optimization vs. conventional design

Orthopedic plates are commonly used after osteotomies for temporary fixation of bones. Patient-specific plates have recently emerged as a promising fixation device. However, it is unclear how various strategies used for the design of such plates perform in comparison with each other. Here, we compare the biomechanical performance of 3D...

Validation and optimization of Patient-specific orthopedic plate design for proximal femur fixation in slipped capital femoral epiphysis patients

Slipped capital femoral epiphysis (SCFE) is a condition in adolescents affecting the proximal femur. Increased mechanical forces result in fracture of the growth plate. Factors increasing the mechanical forces include for example obesity and endocrine disorders. As a result of the fracture a shift of the bone shaft towards the femur head occurs,...

Semi-automated digital workflow to design and evaluate patient-specific mandibular reconstruction implants

The reconstruction of large mandibular defects with optimal aesthetic and functional outcomes remains a major challenge for maxillofacial surgeons. The aim of this study was to design patient-specific mandibular reconstruction implants through a semi-automated digital workflow and to assess the effects of topology optimization on the...

Optimization-based strut-and-tie model generation for reinforced concrete structures under multiple load conditions

Strut-and-Tie modelling (STM) has been widely applied to design D-regions of reinforced concrete structures. For economic and environmental reasons there is a need for optimized Strut-and-Tie models. How to optimize Strut-and-Tie models considering multiple load combinations has not been investigated extensively in the literature. In order to...

Development of a Workflow for Designing Patient-Specific Mandibular Reconstruction Implants and Predicting their Performance through Experimentally Validated Finite Element Models

Restoration of the normal mandibular form and function is attempted with reconstructive surgery. The current standard procedure to restore continuity defects of the mandible involves free tissue transfer with an autologous bone flap. Even though the success rates are high, several critical drawbacks have been associated with this procedure,...

Automated optimization-based generation and quantitative evaluation of Strut-and-Tie models

Strut-and-Tie modelling (STM) is a well-known approach to design D-regions in reinforced concrete structures. Because the STM method is based on lower-bound analysis, finding a suitable truss-analogy model is the most important aspect to guarantee good structural and economic performance of a resulting design. Continuum topology optimization ...

Compliant Fluidic Control Structures: Concept and synthesis approach

The concept and synthesis approach for planar Compliant Fluidic Control Structures (CFCSs), monolithic flexible continua with embedded functional pores, is presented in this manuscript. Such structures are envisioned to find application in biomedicine as tunable microfluidic devices for drug/nutrient delivery. The functional pores enlarge and...