An Accelerator for Posit Arithmetic Targeting Posit Level 1 BLAS Routines and Pair-HMM

The newly proposed posit number format uses a significantly different approach to represent floating point numbers. This paper introduces a framework for posit arithmetic in reconfigurable logic that maintains full precision in intermediate results. We present the design and implementation of a L1 BLAS arithmetic accelerator on posit vectors...

Accelerating DNA Variant Calling Algorithms on High Performance Computing Systems

Next generation sequencing (NGS) technologies have transformed the landscape of genomic research. With the significant advances in NGS technologies, DNA sequencing is more affordable and accessible than ever before. Meanwhile, many DNA sequence analysis tools have been developed to derive useful information from the raw sequencing data produced...

Development of vehicle-cyclist interaction model for scenario generation/validation

The number of road accidents is increasing all over the world. When Vulnerable Road Users (VRU) are involved in an accident, they are prone to more serious injuries. Half of the fatalities around the world involve VRUs. One way of mitigating the severity and the number of VRU accidents is the introduction of Advanced Driver Assistance Systems ...

Efficient Acceleration of the Pair-HMMs Forward Algorithm for GATK HaplotypeCaller on Graphics Processing Units

GATK HaplotypeCaller (HC) is a popular variant caller, which is widely used to identify variants in complex genomes. However, due to its high variants detection accuracy, it suffers from long execution time. In GATK HC, the pair-HMMs forward algorithm accounts for a large percentage of the total execution time. This article proposes to...

Zoekfunctionaliteit StamboomNederland

In opdracht van het bedrijf 42 is er een nieuwe zoekfunctionaliteit ontwikkelt voor het systeem StamboomNederland, dit systeem is in opdracht van het Centraal Bureau voor Genealogie (CBG) ontwikkelt door 42. Het systeem bevat genealogische data voor het bijhouden van stambomen. De huidige zoekfunctionaliteit werkt echter niet naar behoren...