- document
-
Beets, Josine (author)Incorporating living cells into a non-living matrix is one of the many possible steps that can be undertaken to stop climate change. Especially, photosynthetic organisms have a promising future in material design as they can capture atmospheric carbon dioxide and ’ breathe’ oxygen. This research dives into unravelling the properties of a...master thesis 2023
- document
- Kuo, Chihao (author) master thesis 2023
- document
-
Schwab, Andrea (author), Wesdorp, Marinus A. (author), Xu, J. (author), Abinzano, Florencia (author), Loebel, Claudia (author), Levato, Riccardo (author), Eglin, David (author), Narcisi, Roberto (author), Malda, Jos (author), van Osch, G.J.V.M. (author)Background: The use of acellular hydrogels to repair osteochondral defects requires cells to first invade the biomaterial and then to deposit extracellular matrix for tissue regeneration. Due to the diverse physicochemical properties of engineered hydrogels, the specific properties that allow or even improve the behaviour of cells are not yet...journal article 2023
- document
-
Chen, Yuanyuan (author), Dai, Hanqing (author), Hu, Zhe (author), Wei, Jinxin (author), Zhou, Wenjie (author), Duan, Zhongtao (author), Cui, Zhongjie (author), Wei, Wei (author), Zhang, Kouchi (author)Hydrogel materials have biocompatibility, flexibility, transparency, self-healing ability, adhesion with various substrates, anti-freeze ability, and high-temperature resistance. However, the existing hydrogel devices cannot continue to operate in the case of damage, and they cannot work during the repair period, which brings great challenges...journal article 2023
- document
-
Wang, Hucheng (author), Fu, Xiaoming (author), Gu, Guanyao (author), Bai, Shengyu (author), Li, Runlai (author), Zhong, Weimin (author), Guo, Xuhong (author), Eelkema, R. (author), van Esch, J.H. (author), Cao, Zhixing (author), Wang, Yiming (author)Living organisms are capable of dynamically changing their structures for adaptive functions through sophisticated reaction-diffusion processes. Here we show how active supramolecular hydrogels with programmable lifetimes and macroscopic structures can be created by relying on a simple reaction-diffusion strategy. Two hydrogel precursors ...journal article 2023
- document
-
Jahanmard, F. (author), Khodaei, A. (author), Flapper, Jasper (author), Dogan, O. (author), Roohi, K. (author), Taheri, P. (author), Weinans, H.H. (author), Storm, G. (author), Croes, M. (author), Mastrobattista, E. (author), Amin Yavari, S. (author)Despite being the most widely used biomaterials in orthopedic surgery, metallic implants do not induce new bone growth because they are bioinert. Surface biofunctionalization of implants with immunomodulatory mediators is a recent approach to promote osteogenic factors that facilitate bone regeneration. Liposomes (Lip) can be used as a low-cost,...journal article 2023
- document
-
Chen, Yuanyuan (author), Dai, Hanqing (author), Yan, Yukun (author), Piao, Zhiyan (author), Lu, Hanxu (author), Hu, Zhe (author), Wei, Wei (author), Zhang, Kouchi (author), Zhang, Wanlu (author), Guo, Ruiqian (author)In recent years, various functional fabrics capable of responding to multistimuli have been widely recognized as promising wearable devices. However, the obtained composite functional fabrics have only been applied in a few scenarios, rendering the achievement of multifunctional wearable application scenarios a difficult goal. Therefore,...journal article 2023
- document
-
Oh, J.J. (author), Ammu, S.K. (author), Vriend-Harwig, V.D. (author), Kieffer, R.Y. (author), Dr. Kleiner, F.K. (author), Balasubramanian, S. (author), Karana, E. (author), Masania, K. (author), Aubin-Tam, M.E. (author)Engineered living materials (ELMs) are a novel class of functional materials that typically feature spatial confinement of living components within an inert polymer matrix to recreate biological functions. Understanding the growth and spatial configuration of cellular populations within a matrix is crucial to predicting and improving their...journal article 2023
- document
-
Breve, T. (author)Smart materials are materials that are capable of responding in a programmable and predictive manner. Such materials respond to a broad variety of internal and external triggers and modulate one or more material properties accordingly. Common material responses are controlled release, color changes, morphological changes or changing the...doctoral thesis 2022
- document
-
de Graaf, G. (author), Vriesendorp, Maurits Frans (author), Amin Hassan, H.M. (author), French, P.J. (author)In this research fluorescent optochemical pH probes for the detection of ischaemia have been investigated. Myocardial ischaemia is the most prominent risk during heart surgery. During open heart surgery the heart is temporarily arrested and, since there no blood flowing, oxygen supply and removal of waste products is stopped and heart cells...journal article 2022
- document
-
Zhou, Liangbin (author), Guo, Peng (author), D'Este, Matteo (author), Tong, Wenxue (author), Xu, Jiankun (author), Yao, Hao (author), Stoddart, Martin J. (author), van Osch, G.J.V.M. (author), Ho, Kevin Ki Wai (author), Li, Zhen (author), Qin, Ling (author)Articular cartilage (AC) is an avascular and flexible connective tissue located on the bone surface in the diarthrodial joints. AC defects are common in the knees of young and physically active individuals. Because of the lack of suitable tissue-engineered artificial matrices, current therapies for AC defects, especially full-thickness AC...review 2022
- document
-
Zhang, M. (author), Warth, T. (author), Boon, N.J.H. (author), Demirörs, Ahmet Faik (author), Eral, H.B. (author)A microfluidic platform for continuous synthesis of hydrogel microparticles with superparamagnetic colloids (SPCs) embedded at prescribed positions is described. The shape of the cross-linked microparticle is independently controlled by stop–flow lithography, whereas the position of trapped SPCs are dictated by virtual magnetic moulds made of...journal article 2022
- document
-
Liu, Q. (author), Muralidharan, A. (author), Saateh, A. (author), Ding, Z. (author), ten Dijke, Peter (author), Boukany, P. (author)In the research of cancer cell invasion and metastasis, recreation of physiologically relevant and faithful three-dimensional (3D) tumor models that recapitulate spatial architecture, spatiotemporal control of cell communication and signaling pathways, and integration of extracellular cues remains an open challenge. Here, a programmable...journal article 2022
- document
-
Neves Leal Costa, B. (author), Adão, Ricardo M.R. (author), Maibohm, Christian (author), Accardo, A. (author), Cardoso, Vanessa F. (author), Nieder, Jana B. (author)Biomimicking biological niches of healthy tissues or tumors can be achieved by means of artificial microenvironments, where structural and mechanical properties are crucial parameters to promote tissue formation and recreate natural conditions. In this work, three-dimensional (3D) scaffolds based on woodpile structures were fabricated by two...journal article 2022
- document
-
Berkhout, Willemijn (author)Three-dimensional (3D) bioprinting studies the initial condition of printed constructs, which makes construct static, and neglects the dynamic changes in natural tissue conformation during tissue repair, disease progression and regeneration processes. Therefore, the concept of four-dimensional (4D) bioprinting has been introduced that allows for...master thesis 2021
- document
-
Fan, B. (author)This thesis describes the experimental development of new dynamic hydrogels based on reversible thiol conjugate additions. Redox-controlled hydrogels and self-healing injectable hydrogels have been achieved by introducing reversible thiol conjugate additions to crosslink polymers, leading to hydrogel formation. The overall objective in this...doctoral thesis 2021
- document
-
Somerwil, Flip (author)The goal of this study is to create a phantom which can be used to test strategies for sealing the vaginal cavity, so that ultrasound gel can be used to fill the vaginal cavity improve the visibility of the vaginal cavity in MR-images.<br/>Silicone rubber and PolyVinyl Alcohol (PVA) were tested, to check whether their mechanical properties can...master thesis 2021
- document
-
Lakshminarayanan, Vasudevan (author), Chockalingam, Cindhuja (author), Mendes, E. (author), van Esch, J.H. (author)Properties such as shear modulus, gelation time, structure of supramolecular hydrogels are strongly dependent on self-assembly, gelation triggering mechanism and processes used to form the gel. In our work we extend reported rheology analysis methodologies to pH-triggered supramolecular gels to understand structural insight using a model...journal article 2021
- document
-
Aimi, M. A.Raden Maizatul (author), Hamidah, M. S. (author), Kartini, K. (author), Hana, H. Noor (author), Khalilah, A. K. (author), Schlangen, E. (author)Autonomous healing by the microbially induced calcite precipitation (MICP) mechanism has garnered significant interest in the sustainable approach to concrete repair and maintenance. Previous research works have reported that Bacillus pasteurii and Bacillus sphaericus are the most commonly used in concrete associated with bacteria. However,...journal article 2021
- document
-
Pfaff, N.M. (author), Kleijn, J. Mieke (author), van Loosdrecht, Mark C.M. (author), Kemperman, Antoine J.B. (author)The properties of biofilm EPS are determined by the multiple interactions between its constituents and the surrounding environment. Because of the high complexity of biofilm EPS, its constituents' characterisation is still far from thorough, and identification of these interactions cannot be done yet. Therefore, we use gels of bacterial...journal article 2021