Iron oxide nanoparticles as carriers for the Dy-166/Ho-166 in vivo generator: A study into the characteristics and retention of Dy and Ho in iron oxide nanoparticles

Background:<br/>Cancer is one of the leading causes of death worldwide. Targeted radionuclide therapy has become a important treatment, this is when a carrier molecule is attached to a radionuclide to deliver cytotoxic radiation levels to diseased cells. β<br/>− emitters are frequently used in RNT because they have a long penetration depth, such...

Polymeric micelles as carriers for a 166Dy/166Ho in vivo generator

Cancer is one of the leading causes of death in the world. Because of this, there are many novel methods to treat it being currently researched. One of the answers from the nuclear medicine perspective is Radionuclide Therapy, where alpha or beta emitters are applied, with the goal to selectively irradiate tumours in the...

Core–shell structured gold nanoparticles as carrier for ¹⁶⁶Dy/¹⁶⁶Ho in vivo generator

Background: Radionuclide therapy (RNT) has become a very important treatment modality for cancer nowadays. Comparing with other cancer treatment options, sufficient efficacy could be achieved in RNT with lower toxicity. β⁻ emitters are frequently used in RNT due to the long tissue penetration depth of the β⁻ particles....