Depth resolved quantitative profiling of stratum corneum lipids and water content using short-wave infrared spectroscopy

We show the feasibility of short wave infrared spectroscopy combined with tape stripping as a simple and noninvasive method for the analysis of lipids and the degree of hydration as a function of depth in the stratum corneum. The spectroscopic method utilizes differential detection with three wavelengths 1720, 1750, and 1770 nm, corresponding...

Quantification of changes in skin hydration and sebum after tape stripping using infrared spectroscopy

Skin barrier function relies on well balanced water and lipid system of stratum corneum. Optimal hydration and oiliness levels are indicators of skin health and integrity. We demonstrate an accurate and sensitive depth profiling of stratum corneum sebum and hydration levels using short wave infrared spectroscopy in the spectral range around...