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Automated Detection of Patient-Ventilator Asynchrony in Mechanically Ventilated Patients

de Bie, Melissa (author)

Introduction<br/>Patient-ventilator asynchrony (PVA) poses a significant challenge in the management of mechanically ventilated patients, contributing to adverse clinical outcomes. Current methods of detecting PVA rely on visual assessment by clinicians, leading to subjectivity and inconsistency. Therefore, there is a need for automated...

master thesis 2024

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Predicting Haemodynamic Instability in Critical Congenital Heart Disease Patients: A Proof of Concept

van Winden, Brian (author)

Introduction<br/>Approximately 9 in 1000 children are born with congenital heart disease (CHD), of whom a quarter are classified as critical CHD (CCHD) and require an intervention within their first year. Monitoring these patients in the Paediatric Intensive Care Unit (PICU) is crucial, yet with increasing amounts of data, detecting subtle...

master thesis 2024

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The Power of Flow-Controlled Mechanical Ventilation: Advancing Lung-Protective Ventilation and Respiratory Monitoring in the Intensive Care Unit

Francovich, Juliette (author)

Many patients in the intensive care unit (ICU) depend on mechanical ventilation due to conditions such as severe lung disease, traumatic brain injury, or postoperative coma. While mechanical ventilation is a potentially life-saving intervention, it also has harmful side effects. Especially in patients with lung disease, such as the acute...

master thesis 2024

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Anomaly Detection in Sleep Staging in Critically Ill Children

Oerlemans, Carlijn (author)

Study objectives: Conventional sleep scoring is based on the scoring criteria of the American Association of Sleep Medicine (AASM) but may not be suited to describe sleep in critically ill children admitted to the Pediatric Intensive Care Unit (PICU). In this study, an anomaly detection model using Gaussian Models trained on sleep stages in data...

master thesis 2024

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Validation of a hand hygiene visual feedback system to improve compliance with drying time of alcohol-based hand rub in a neonatal intensive care unit: the Incubator Traffic Light system

van Gils, R.H.J. (author), Kornelisse, R. F. (author), Dankelman, J. (author), Helder, O. K. (author)

Background: Compliance with the recommended 30 s drying time of alcohol-based hand rub (ABHR) is often suboptimal. To increase hand hygiene compliance at a neonatal intensive care unit (NICU), we installed an Incubator Traffic Light (ITL) system which shows ‘green light’ to open incubator doors after the recommended drying time. Aim: To...

journal article 2024

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Development of a Web-Based Oxygenation Dashboard for Preterm Neonates: A Quality Improvement Initiative

Poppe, J. A. (author), Smorenburg, R. S. (author), Goos, T.G. (author), Taal, H. R. (author), Reiss, I. K.M. (author), Simons, S. H.P. (author)

Background: Preterm neonates are extensively monitored to require strict oxygen target attainment for optimal outcomes. In daily practice, detailed oxygenation data are hardly used and crucial patterns may be missed due to the snapshot presentations and subjective observations. This study aimed to develop a web-based dashboard with both...

journal article 2024

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Towards Greener ICUs: Redesigning the Use of Disposable Gloves

van den Berg, Lisanne (author), Albayrak, A. (author), Hunfeld, Nicole (author), Diehl, J.C. (author)

This research and design project is part of the Green ICU initiative and focused on reducing the environmental impact of gloves at the Intensive Care Unit (ICU) of the Erasmus Medical Center (EMC). At the ICU of the EMC around 108 gloves are used per patient per day; to protect the user (healthcare staff) from infections. The high frequency of...

conference paper 2024

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Towards Circular ICUs: Circular Intubations as a Catalyser for Systemic Change

Ville, Alicia (author), Hunfeld, Nicole (author), Bakker, C.A. (author), Sené, Baptiste (author), Diehl, J.C. (author)

This project aims to reduce the environmental impact of the Intensive Care Unit (ICU) of the Erasmus Medical Center (EMC). Systemic design research was executed to map the current waste flow created by the ICU. Literature review, interviews and observations were performed to gather information about the healthcare protocols, hospital procurement...

conference paper 2024

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Respiratory rate monitoring in ICU patients and healthy volunteers using electrical impedance tomography: a validation study

Wisse, J. J. (author), Flinsenberg, M. J.W. (author), Jonkman, A. H. (author), Goos, T.G. (author), Gommers, D.A.M.P.J. (author)

Objective. The respiratory rate (RR) is considered one of the most informative vital signals. A well-validated standard for RR measurement in mechanically ventilated patient is capnography; a noninvasive technique for expiratory CO2measurements. Reliable RR measurements in spontaneously breathing patients remains a challenge as continuous...

journal article 2024

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Quantifying Cerebral Autoregulation in Children with Severe Traumatic Brain Injury

Robles, Tahisa (author)

master thesis 2023

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Electroencephalography Monitoring in the Critically Ill: Towards a More Efficient and Effective Monitoring Strategy

Verboom, Marit (author)

Critically ill patients in the Intensive Care Unit (ICU) are often comatose and thoroughly monitored. Neurological complications occur in up to 20% of these patients. Therefore, monitoring of the brain, which can be performed using electroencephalography (EEG), has the potential to significantly impact the outcomes of patients at the ICU....

master thesis 2023

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Continuous Multimodal Monitoring of Neonates with a Congenital Diaphragmatic Hernia

Keulen, Bart (author)

Introduction: Congenital diaphragmatic hernia (CDH) is a rare developmental defect of the diaphragm characterised by herniation of abdominal organs into the thoracic cavity during prenatal development. This herniation is usually accompanied by pulmonary hypertension (PH) and cardiac dysfunction (CD). Although several parameters are known to...

master thesis 2023

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Identifying observer-based features for seizure detection in 4-electrode EEG in the paediatric ICU

Lange, Sanne (author)

Epilepsy has been reported in 10-40% of children in the paediatric intensive care unit (PICU). Amplitude-integrated electroencephalography (aEEG), often used as neuromonitoring in the PICU, has some limitations and as a result, caretakers in the PICU may find it challenging to interpret aEEG. This may lead to uncertainty during diagnosis and...

master thesis 2023

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Predicting Beta-Lactam Target Non-Attainment in ICU Patients at Treatment Initiation: Development and External Validation of Three Novel (Machine Learning) Models

Wieringa, André (author), Ewoldt, Tim (author), Gangapersad, Ravish N. (author), Gijsen, Matthias (author), Parolya, N. (author), Kats, Chantal J. A. R. (author), Spriet, Isabel (author), Endeman, Henrik (author), Haringman, Jasper J. (author)

In the intensive care unit (ICU), infection-related mortality is high. Although adequate antibiotic treatment is essential in infections, beta-lactam target non-attainment occurs in up to 45% of ICU patients, which is associated with a lower likelihood of clinical success. To optimize antibiotic treatment, we aimed to develop beta-lactam target...

journal article 2023

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Improving the quality of the acoustic environment in neonatal intensive care units: a review of scientific literature and technological solutions

Lenzi, Sara (author), Spagnol, S. (author), Ozcan Vieira, E. (author)

There is an increased awareness of how the quality of the acoustic environment impacts the lives of human beings. Several studies have shown that sound pollution has adverse effects on many populations, from infants to adults, in different environments and workplaces. Hospitals are susceptible environments that require special attention since...

review 2023

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The Development of a Dashboard to Optimise Neuromonitoring of Paediatric Traumatic Brain Injury Patients in the Intensive Care Unit

Formsma, Bart (author)

<b>Introduction</b> Traumatic brain injury (TBI) is a leading cause of childhood morbidity, disability and mortality worldwide. In the treatment of TBI, neuromonitoring is essential to prevent secondary neurological damage. However, the use of neuromonitoring and specifically therapeutic targets is currently limited evidence-based.<br/><b...

master thesis 2022

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Improving the daily ICU experience from a critically ill patient's perspective

van Houwelingen, Eva (author)

The intensive care unit (ICU) is a dehumanizing technical environment causing complications that are all captured in the term post-intensive-care syndrome (PICS). The patient’s well-being could be improved by moving away from this hostile environment toward more patient-centred care. Therefore this report explores how to improve the daily ICU...

master thesis 2022

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Reducing the environmental impact of syringes in the Intensive Care Unit

Honkoop, Margot (author)

This graduation project focused on reducing the environmental impact of syringes on the Intensive Care Unit (ICU) of Erasmus University Medical Centre (MC) by designing solutions based on circular economy.<br/><br/>The ICU of Erasmus MC produces an excessive amount of waste and initiated the transition towards a circular ICU. Syringes and their...

master thesis 2022

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Circular material flow in the intensive care unit—environmental effects and identification of hotspots

Hunfeld, Nicole (author), Diehl, J.C. (author), Timmermann, Maarten (author), van Exter, Pieter (author), Bouwens, Joris (author), Browne-Wilkinson, Savanna (author), de Planque, Nine (author), Gommers, D.A.M.P.J. (author)

Purpose: The healthcare sector is responsible for 6–7% of CO₂ emissions. The intensive care unit (ICU) contributes to these CO₂ emissions and a shift from a linear system to a circular system is needed. The aim of our research was to perform a material flow analysis (MFA) in an academic ICU. Secondary aims were to obtain...

journal article 2022

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An Algorithm for Automatic Acoustic Alarm Recognition in the Neonatal Intensive Care Unit

Spagnol, S. (author), Goos, T.G. (author), Reiss, Irwin (author), Ozcan Vieira, E. (author)

Inside the Neonatal Intensive Care Unit (NICU), exposure to loud sounds such as acoustic medical alarms can have adverse effects on neonates, parents, and medical staff. With the aim of having an accurate overview of which and how often acoustic medical alarms occur, this paper presents a simple signal processing-based approach for detecting...

conference paper 2022