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van Bijsterveldt, Jermo (author)Kenzo Tange, a prominent architect and figure in the Metabolism movement, played a significant role in shaping Japanese architecture. His designs often combined modernism with traditional Japanese styles, incorporating Metabolist principles such as the use of multiple towers and sky corridors for traffic flow. The Japan World Exhibition in Osaka...student report 2024
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Oei, Kevin (author)After the second world war two movements evolved as a reaction to the developments the war brought into society and built environment. The comparison involves the movements metabolism and structuralism both from the lenses of the protagonists of these movements: Kenzo Tange and Herman Hertzberger respectively. <br/>This thesis aims for an...student report 2024
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Alwani, Neil (author)This study investigates the application of generative models for synthetic data generation in pathway optimization experiments within the field of metabolic engineering. Conditional Variational Autoencoders (CVAEs) use neural networks and latent variable distributions to generate new, plausible data samples. We adapt this model by conditioning...bachelor thesis 2024
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Kirbeyi, Doruk (author)This research explores the landscape of dataset generation through the lens of Probabilistic Principal Component Analysis (PPCA) and β-Conditional Variational Auto-encoder (β-CVAE) models. We conduct a comparative analysis of their respective capabilities in reproducing datasets that mirror the distribution of the original data that comes from a...bachelor thesis 2024
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Páez Watson, T.W. (author), van Loosdrecht, Mark C.M. (author), Wahl, S.A. (author)With the rapid growing availability of metagenome assembled genomes (MAGs) and associated metabolic models, the identification of metabolic potential in individual community members has become possible. However, the field still lacks an unbiassed systematic evaluation of the generated metagenomic information to uncover not only metabolic...journal article 2024
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Jaroensuk, Juthamas (author), Sutthaphirom, Chalermroj (author), Phonbuppha, Jittima (author), Chinantuya, Wachirawit (author), Kesornpun, Chatchai (author), Akeratchatapan, Nattanon (author), Kittipanukul, Narongyot (author), Phatinuwat, Kamonwan (author), Hollmann, F. (author)Cofactor imbalance obstructs the productivities of metabolically engineered cells. Herein, we employed a minimally perturbing system, xylose reductase and lactose (XR/lactose), to increase the levels of a pool of sugar phosphates which are connected to the biosynthesis of NAD(P)H, FAD, FMN, and ATP in Escherichia coli. The XR/lactose system...journal article 2024
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Allaart, M.T. (author), Korkontzelos, Charilaos (author), Sousa, Diana Z. (author), Kleerebezem, R. (author)Syngas fermentation has gained momentum over the last decades. The cost-efficient design of industrial-scale bioprocesses is highly dependent on quantitative microbial growth data. Kinetic and stoichiometric models for syngas-converting microbes exist, but accurate experimental validation of the derived parameters is lacking. Here, we...journal article 2024
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Yarali, E. (author), Klimopoulou, M. (author), David, M.K. (author), Boukany, P. (author), Staufer, U. (author), Fratila-Apachitei, E.L. (author), Zadpoor, A.A. (author), Accardo, A. (author), Mirzaali, Mohammad J. (author)The Poisson's ratio and elastic modulus are two parameters determining the elastic behavior of biomaterials. While the effects of elastic modulus on the cell response is widely studied, very little is known regarding the effects of the Poisson's ratio. The micro-architecture of meta-biomaterials determines not only the Poisson's ratio but...journal article 2024
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Plastic particles affect N2O release via altering core microbial metabolisms in constructed wetlandsYang, X. (author), Chen, Yi (author), Liu, Tao (author), Zhang, Lu (author), Wang, Hui (author), Chen, Mengli (author), He, Qiang (author), Liu, G. (author), Ju, Feng (author)Constructed wetlands (CWs) have been proven to effectively immobilize plastic particles. However, little is known about the differences in the impact of varying sized plastic particles on nitrous oxide (N<sub>2</sub>O) release, as well as the intervention mechanisms in CWs. Here, we built a lab-scale wetland model and introduced plastic...journal article 2024
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van den Broek, M.A. (author), Ortiz Merino, R.A. (author), Bennis, N.X. (author), Wronska, A.K. (author), Else-Hassing, J. (author), Daran-Lapujade, P.A.S. (author), Daran, J.G. (author)The biobased-economy aims to create a circular biotechnology ecosystem to transition from a fossil fuel-based to a sustainable industry based on biomass. For this, new microbial cell-factories are essential. We present the draft genome of the CEN.PK-derived Saccharomyces cerevisiae SpyCas9 expressing strain (IMX2600), that serve as chassis of...journal article 2024
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Shomar, Helena (author), Bokinsky, G.E. (author)Reactions catalysed by iron-sulfur (Fe-S) enzymes appear in a variety of biosynthetic pathways that produce valuable natural products. Harnessing these biosynthetic pathways by expression in microbial cell factories grown on an industrial scale would yield enormous economic and environmental benefits. However, Fe-S enzymes often become...review 2024
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Almeida Benalcazar, E.F. (author)The mitigation of global warming requires an urgent shift from the fossil fuel-based productive matrix currently in place. Technological platforms are being developed to reduce the amount of carbon of fossil origin, which is emitted to the atmosphere as a side-product from the production of energy. Gas mixtures containing CO, H2 and CO2 are...doctoral thesis 2023
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Bakker, Yannick (author)The research and design hypothesize how data centers can complement the urban environment rather than make a negative impact, both environmentally and spatially. Data centers consume and produce a variety of valuable flows, ranging from electricity, cooling/heating and water use. The aim of the research is to discover whether it is possible to...master thesis 2023
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van Aalst, A.C.A. (author)The production of ethanol by the yeast Saccharomyces cerevisiae remains the process in industrial biotechnology with the largest product volume (ca. 100 million litres annually in 2022). Carbon losses occur due to the formation of biomass and glycerol, which can account for at least 8% of the product. Under anaerobic conditions, formation of...doctoral thesis 2023
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Christofi, Andreas (author)Dating back to 10,000 B.C.E., fermentation has served as a vital tool primarily for food preservation. In the nineteenth century, Louis Pasteur put forth the proposition that the occurrence of fermentation is predominantly facilitated by the presence of microorganisms. Pasteur’s discovery spurred comprehensive studies on microorganisms,...master thesis 2023
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Liu, Shiru (author)This thesis explores spatial strategies for achieving sustainable industry transition in the dispersed urbanised areas of the Greater Bay Area (GBA) in China. Since 1978, urbanisation in the GBA has accelerated, significantly expanding beyond metropolitan regions. These dispersed areas, described as the Desakota by Terry McGee, encompass a...master thesis 2023
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Kolmas, Mats (author)This paper investigates the potential of passively lowering the operational energy requirement of performance buildings in the Central European Climate. The energy consumption of this typology is largely caused by mechanical ventilation to cool and ventilate the theatre during shows, necessary for the thermal comfort and ventilation requirements...master thesis 2023
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Chang, Nicole (author)The coast of Paramaribo is predicted to undergo urban expansion due to the growing population of Paramaribo. However, the coast has to do with several challenges; tidal- and urban flooding and coastal erosion. This does not make the coast the most habitable place for urban expansion. The urban, water and soil systems are not functioning in...master thesis 2023
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Joshi, Sumeet (author)As technology advances and materials evolve, architects and designers have access to innovative tools such as digital fabrication, robotic production, CNC milling, and artificial intelligence. These tools have made them more resourceful and precise in their work, allowing them to constantly exceed the potentials and find solutions to future...student report 2023
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Boenders, Arne (author)How will we live together? With this graduation project a strategy has been developed to transform vacant heritage into cyclifiers, buildings that have a positive impact on their environment by creating a way of living together in balance with nature, humans, and buildings. Social public functions with a focus on healthy living, as well as a...master thesis 2023