Searched for: subject%3A%22Osteoarthritis%22
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Ferrao Blanco, Mauricio N. (author), Bastiaansen-Jenniskens, Yvonne M. (author), Chambers, Mark G. (author), Pitsillides, Andrew A. (author), Narcisi, Roberto (author), van Osch, G.J.V.M. (author)
Objective: In osteoarthritis, chondrocytes tend to acquire a hypertrophic phenotype, which contributes to the modification of the extracellular matrix, resulting in permanent cartilage changes. In mouse chondrocytes, pro-inflammatory macrophages and pro-inflammatory cytokines have been shown to stimulate hypertrophy via the activation of the...
journal article 2021
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de Visser, Huub M. (author), Sanchez, Christelle (author), Mastbergen, Simon C. (author), Lafeber, Floris P.J.G. (author), Henrotin, Yves E. (author), Weinans, Harrie (author)
Objective: Fibulin-3 is a glycoprotein highly expressed in osteoarthritic cartilage and inhibits angiogenesis and chondrocyte differentiation. Recent studies have indicated that fibulin-3 has potential value as a biomarker in osteoarthritis. The aim of the present study is to examine the role of 3 fibulin-3 peptides (Fib3-1, Fib3-2, and Fib3...
journal article 2019
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Karatsidis, Angelos (author), Richards, Rosie E. (author), Konrath, Jason M. (author), Van Den Noort, Josien C. (author), Schepers, H. Martin (author), Bellusci, Giovanni (author), Harlaar, J. (author), Veltink, Peter H. (author)
Background: Gait retraining interventions using real-time biofeedback have been proposed to alter the loading across the knee joint in patients with knee osteoarthritis. Despite the demonstrated benefits of these conservative treatments, their clinical adoption is currently obstructed by the high complexity, spatial demands, and cost of...
journal article 2018
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Cudejko, Tomasz (author), Van Der Esch, Martin (author), Schrijvers, Jim (author), Richards, Rosie (author), Van Den Noort, Josien C. (author), Wrigley, Tim (author), Van Der Leeden, Marike (author), Roorda, Leo D. (author), Lems, Willem (author), Harlaar, J. (author), Dekker, Joost (author)
Objectives Wearing a soft knee brace has been shown to reduce self-reported knee instability in persons with knee OA. There is a need to assess whether a soft knee brace has a beneficial effect on objectively assessed dynamic knee instability as well. The aims of the study were to evaluate the effect of a soft knee brace on objectively...
journal article 2018
Searched for: subject%3A%22Osteoarthritis%22
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