Image Acquisition and Attenuation Map Estimation for Multi-pinhole Clinical SPECT

Single-photon emission computed tomography (SPECT) is a well-established nuclear imaging modality for studying functional and pathological properties of the brain. Conventional general purpose SPECT systems typically offer a spatial resolution of about 10 mm with a sensitivity of 0.01-0.02%. A few dedicated brain SPECT scanners have been...

Multi-pinhole Molecular Breast Tomosynthesis: from Simulation to Prototype

Breast cancer, being the most common cancer among females, is nowadays routinely diagnosed using X-ray mammography. Though this technique has proven its effectiveness in many cases, X-ray mammography has some disadvantages like reduced diagnostic sensitivity for dense breasts, need for strong breast compression and inability to assess tissues at...

Characterization of a multi-pinhole molecular breast tomosynthesis scanner

In recent years, breast imaging using radiolabelled molecules has attracted significant interest. Our group has proposed a multi-pinhole molecular breast tomosynthesis (MP-MBT) scanner to obtain 3D functional molecular breast images at high resolutions. After conducting extensive optimisation studies using simulations, we here present a first...