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Ooms, Eline (author)Lacunes of presumed vascular origin (lacunes) are small lesions in the brain and are an important indicator of cerebral small vessel disease (cSVD). To gain more insight in this disease, obtaining more information about the shape, size and location of lacunes is essential. However, manual segmentation (the voxel-wise labeling of lacunes in a...master thesis 2021
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van Arendonk, Joyce (author), Yilmaz, Pinar (author), Steketee, Rebecca (author), Zijlmans, Jendé L. (author), Lamballais, Sander (author), Niessen, W.J. (author), Neitzel, Julia (author), Ikram, M. Arfan (author), Vernooij, Meike W. (author)Brain pathology develops at different rates between individuals with similar burden of risk factors, possibly explained by brain resistance. We examined if education contributes to brain resistance by studying its influence on the association between vascular risk factors and brain pathology. In 4111 stroke-free and dementia-free community...journal article 2021
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Leeuwis, Anna E. (author), Hooghiemstra, Astrid M. (author), Bron, Esther E. (author), Kuipers, Sanne (author), Oudeman, Eline A. (author), Kalay, Tugba (author), Niessen, W.J. (author)Introduction: We examined the role of hemodynamic dysfunction in cognition by relating cerebral blood flow (CBF), measured with arterial spin labeling (ASL), to cognitive functioning, in patients with heart failure (HF), carotid occlusive disease (COD), and patients with cognitive complaints and vascular brain injury on magnetic resonance...journal article 2020
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Hooghiemstra, Astrid M. (author), Bertens, Anne Suzanne (author), Leeuwis, Anna E. (author), Bron, Esther E. (author), Bots, Michiel L. (author), Brunner-La Rocca, Hans Peter (author), De Craen, Anton J M (author), van der Geest, Rob J. (author), Greving, Jacoba P. (author), Kappelle, L. Jaap (author), Niessen, W.J. (author), van Oostenbrugge, Robert J. (author), van Osch, Matthias J P (author), de Roos, Albert (author), van Rossum, Albert C. (author), Biessels, Geert Jan (author), van Buchem, Mark A. (author), Daemen, Mat J A P (author), van der Flier, Wiesje M. (author)Background: Hemodynamic balance in the heart-brain axis is increasingly recognized as a crucial factor in maintaining functional and structural integrity of the brain and thereby cognitive functioning. Patients with heart failure (HF), carotid occlusive disease (COD), and vascular cognitive impairment (VCI) present themselves with complaints...journal article 2017
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Stijntjes, M. (author), De Craen, Anton J M (author), Van Der Grond, Jeroen (author), Meskers, Carel G M (author), Slagboom, P. Eline (author), Maier, Andrea B. (author)Background: The positive relationship between cognitive and physical performance has been widely established. The influence of brain structure on both domains has been shown as well. Objective: We studied whether the relationship between brain structure and physical performance is independent of cognitive performance. Methods: This was a...journal article 2016