Predicting the Efficacy of Stalk Cells Following Leading Cells Through a Micro-Channel Using Morphoelasticity and a Cell Shape Evolution Model

Cancer cell migration between different body parts is the driving force behind cancer metastasis, which causes mortality of patients. Migration of cancer cells often proceeds by penetration through narrow cavities in possibly stiff tissues. In our previous work [12], a model for the evolution of cell geometry is developed, and in the current...

Using Causal Discovery to Design Agent-based Models

Designing agent-based models is a difficult task. Some guidelines exist to aid modelers in designing their models, but they generally do not include specific details on how the behavior of agents can be defined. This paper therefore proposes the AbCDe methodology, which uses causal discovery algorithms to specify agent behavior. The methodology...

Orientation and Wayfinding: Measuring Visibility

In this chapter, we explain how the analytical logic of space syntax is applied for visibility analysis. In the previous chapter, the focus was on presenting all public spaces as axial sightlines. The individual axial line is a one-dimensional (1D) representation of public space and is useful for analysing the interrelationship of public spaces...

SMART mobility via prediction, optimization and personalization

In this chapter, we present a methodological approach for Smart Mobility that integrates three key features: prediction, optimization, and personalization. They are integrated in such a way that when a travel menu is offered, predicted conditions are considered in the attributes of alternatives and optimized system-level policies are maintained....

Agent-Based Modelling of the Social Dynamics of Energy End-Use

Agent-based modelling and simulation is now accepted as a valuable tool for describing the dynamics of complex socio-technical systems, and for studying complex adaptive systems. This chapter surveys the opportunities and challenges in agent-based models (ABM) for the social dynamics of energy end use. Following an introduction to the...

A complementary understanding of residential energy demand, consumption and services

This chapter explores potential ways to implement, and benefits for policymaking of, the complementary use of two different types of modelling for analysing residential energy consumption and ethnographic research. The more traditional approach of techno-economic modelling is considered alongside agent-based modelling that incorporates both...