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Tseng, C. (author), Jaspers, Jaap (author), Romero, Alejandra Mendez (author), Wielopolski, Piotr (author), Smits, M. (author), van Osch, Matthias J.P. (author), Vos, F.M. (author)The arterial input function (AIF) plays a crucial role in estimating quantitative perfusion properties from dynamic susceptibility contrast (DSC) MRI. An important issue, however, is that measuring the AIF in absolute contrast-agent concentrations is challenging, due to uncertainty in relation to the measured (Formula presented.) -weighted...journal article 2023
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van Schie, J.J.N. (author), Lavini, Cristina (author), van Vliet, L.J. (author), Kramer, Gem (author), Pieters - van den Bos, Indra (author), Marcus, H.J.J. (author), Stoker, Jaap (author), Vos, F.M. (author)Background: Pharmacokinetic (PK) models can describe microvascular density and integrity. An essential component of PK models is the arterial input function (AIF) representing the time-dependent concentration of contrast agent (CA) in the blood plasma supplied to a tissue. Purpose/Hypothesis: To evaluate a novel method for subject-specific...journal article 2018
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Poot, D.H.J. (author), van der Heijden, R.A.J. (author), van Middelkoop, Marienke (author), Oei, Edwin H.G. (author), Klein, S. (author)Purpose: To identify the optimal combination of pharmacokinetic model and arterial input function (AIF) for quantitative analysis of blood perfusion in the patellar bone using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and Methods: This method design study used a random subset of five control subjects from an...journal article 2018