- document
-
Chaker, Layal (author), Cremers, Lotte G M (author), Korevaar, Tim I.M. (author), De Groot, Marius (author), Dehghan, Abbas (author), Franco, Oscar H. (author), Niessen, W.J. (author), Ikram, M. Arfan (author), Peeters, Robin P. (author), Vernooij, Meike W. (author)Thyroid hormone (TH) is crucial during neurodevelopment, but high levels of TH have been linked to neurodegenerative disorders. No data on the association of thyroid function with brain imaging in the general population are available. We therefore investigated the association of thyroid-stimulating hormone and free thyroxine (FT4) with...journal article 2018
- document
-
Papma, Janne M. (author), Smits, Marion (author), De Groot, Marius (author), Mattace-Raso, Francesco U. S. (author), van der Lugt, Aad (author), Vrooman, Henri A. (author), Niessen, W.J. (author), Koudstaal, Peter J. (author), van Swieten, John C. (author), van der Veen, Frederik M. (author), Prins, Niels D. (author)Objectives: Diminished function of the posterior cingulate cortex (PCC) is a typical finding in early Alzheimer’s disease (AD). It is hypothesized that in early stage AD, PCC functioning relates to or reflects hippocampal dysfunction or atrophy. The aim of this study was to examine the relationship between hippocampus function, volume and...journal article 2017
- document
-
Bron, Esther E. (author), Smits, Marion (author), Papma, Janne M. (author), Steketee, Rebecca M E (author), Meijboom, Rozanna (author), De Groot, Marius (author), van Swieten, John C. (author), Niessen, W.J. (author), Klein, S. (author)Objectives: To investigate the added diagnostic value of arterial spin labelling (ASL) and diffusion tensor imaging (DTI) to structural MRI for computer-aided classification of Alzheimer's disease (AD), frontotemporal dementia (FTD), and controls. Methods: This retrospective study used MRI data from 24 early-onset AD and 33 early-onset FTD...journal article 2016