Modulating the inflammatory phenotype of monocyte-derived dendritic cells using osmolality in 3D microenvironments

Delayed healing or non-union of bone fractures are still clinically and economically relevant problems. Bone healing includes pro- and anti-inflammatory phases, which proved crucial for successful healing. Being able to modulate these inflammatory responses could potentially promote bone fracture healing. Dendritic cells play important roles in...

Immunomodulation of surface biofunctionalized 3D printed porous titanium implants

Additive manufacturing (AM) techniques have provided many opportunities for the rational design of porous metallic biomaterials with complex and precisely controlled topologies that give rise to unprecedented combinations of mechanical, physical, and biological properties. These favorable properties can be enhanced by surface...