Magnetic hybrid Pd/Fe-oxide nanoparticles meet the demands for ablative thermo-brachytherapy

Objective: To investigate the potential of hybrid Pd/Fe-oxide magnetic nanoparticles designed for thermo-brachytherapy of breast cancer, considering their specific loss power (SLP) and clinical constraints in the applied magnetic field. Methods: Hybrid nanoparticles consisting of palladium-core and iron oxide shell of increasing thickness,...

Improving iron oxide-based adsorbents for phosphate recovery from surface water using Mössbauer spectroscopy as main analytical tool

This thesis focuses on recycling resources while preserving water quality and availability. This concept is at the basis of a healthy and sustainable society yet works needs to be done. Water scarcity will be a growing challenge that humanity will have to face in the coming years, due to poor resource management and the climate change crisis....

Iron oxide nanoparticles as carriers for the Dy-166/Ho-166 in vivo generator: A study into the characteristics and retention of Dy and Ho in iron oxide nanoparticles

Background:<br/>Cancer is one of the leading causes of death worldwide. Targeted radionuclide therapy has become a important treatment, this is when a carrier molecule is attached to a radionuclide to deliver cytotoxic radiation levels to diseased cells. β<br/>− emitters are frequently used in RNT because they have a long penetration depth, such...

Simulation of temperature and dose distribution of a proposed minimally invasive treatment of early‐stage breast cancer by combining thermal ablation and LDR brachytherapy using Pd-103 SPIO nanoparticles

Treatment of early stage breast cancer is generally invasive to a patient's daily life while being treated. Therefore, to diminish the physical and psychological impact during and after recovery, a newly proposed minimally invasive therapy for early-stage breast cancer treatment is proposed. Within this study, this proposed treatment is modelled...

Magnetic Nanoparticles to Unique DNA Tracers: Effect of Functionalization on Physico-chemical Properties

Abstract: To monitor and manage hydrological systems such as brooks, streams, rivers, the use of tracers is a well-established process. Limited number of potential tracers such as salts, isotopes and dyes, make study of hydrological processes a challenge. Traditional tracers find limited use due to lack of multiplexed, multipoint tracing and...

Potential of MRI in radiotherapy mediated by small conjugates and nanosystems

Radiation therapy has made tremendous progress in oncology over the last decades due to advances in engineering and physical sciences in combination with better biochemical, genetic and molecular understanding of this disease. Local delivery of optimal radiation dose to a tumor, while sparing healthy surrounding tissues, remains a great...