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Willink, Ysbrand (author)Introduction: Pancreatic adenocarcinoma holds one of the worst prognosis of all known malignancies. Local treatment options for patients with unresectable pancreatic cancer may increase tumor control and benefit patient survival. This study aimed to test the feasibility of a possible new treatment method utilizing intratumoral holmium...master thesis 2021
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de Kater, E.P. (author), Sakes, A. (author), Bloemberg, J. (author), Jager, D.J. (author), Breedveld, P. (author)Tissue transport is a challenge during Minimally Invasive Surgery (MIS) with the current suction-based instruments as the increasing length and miniaturisation of the outer diameter requires a higher pressure. Inspired by the wasp ovipositor, a slender and bendable organ through which eggs can be transported, a flexible transport mechanism for...journal article 2021
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Kawasaki, S. (author), Subramaniam, Indulakshmi (author), Saccher, M. (author), Dekker, R. (author)Implantable medical devices are becoming smaller and more deeply implanted in the human body for various applications (i.e., neurostimulation, drug delivery, bone fracture monitoring). Therefore, an efficient ultrasound power transfer link is needed to charge these devices. However, this is challenging because each ultrasound transducer has...conference paper 2021
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Friedericy, Herman J. (author), van Egmond, Cas W. (author), Vogtländer, J.G. (author), van der Eijk, A.C. (author), Jansen, F.W. (author)The widespread use of single-use polypropylene packaging for sterilization of surgical instruments (blue wrap) results in enormous environmental pollution and plastic waste, estimated at 115 million kilograms on a yearly basis in the United States alone. Rigid sterilization containers (RSCs) are a well-known alternative in terms of quality...journal article 2021
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Siddiqi, M.A. (author), Beurskens, Robert H.S.H. (author), Kruizinga, Pieter (author), De Zeeuw, Chris I. (author), Strydis, C. (author)Modern Implantable Medical Devices (IMDs) are vulnerable to security attacks because of their wireless connectivity to the outside world. One of the main security challenges is establishing trust between the IMD and an external reader/programmer in order to facilitate secure communication. Numerous device-pairing schemes have been proposed to...journal article 2021
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Scheepens, Karlijn M.J. (author), Marsidi, Nick (author), Genders, Roel E. (author), Horeman, T. (author)After surgery, around 35% of patients experience problems of excessive scarring, causing disfiguring and impaired function. An incision placed in the wrong direction causes unnecessary skin tension on the wound, resulting in increased collagen disposition and potentially hypertrophic scars. Currently, skin tension lines are used for incision...journal article 2021
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Horsman, Chris (author)In the worlds poorest regions there exists an urgent need for surgical care. Open fractures, one of the Bellwether procedures, are treated in only 42% of the health facilities in low- and middle income countries. Worldwide, external fixation is one of the most important treatment methods for open fractures, providing immobilization to the...master thesis 2020
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Blankensteijn, Charlotte (author)Microcatheters are used for endovascular diagnosis and treatment purposes. Variations of this minimally invasive instrument, accompanied by guidewires, are manipulated through the vasculature towards the target of the intervention. The human vascular anatomy can however present complex pathways towards a target, for example a distal tumor....master thesis 2020
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Schouten, Anneke (author)When in 2008 the financial crisis set it in Europe, consequences for the healthcare systems were inevitable (Parmar, Stavropoulou, & Ioannidis, 2016). Health budgets were reduced, and since the beginning of the crisis, 1.5 million additional people in Europe have had an unmet need for healthcare (A. Reeves, McKee, & Stuckler, 2015). A...master thesis 2020
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Westhoek, Youri (author)Implantable medical devices (IMDs) such as cardiac pacemakers, cochlear implants, and neurostimulators improve millions of people’s lives every day. Over the years, IMDs have significantly improved in function, increased in lifetime, and decreased in size. However, further miniaturisation is limited by the batteries used to power these devices,...master thesis 2020
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van Kleef, Coen (author)Developed market multinational enterprises (DMNEs) and emerging market multinational enterprises (EMNEs) can serve developed and emerging markets via a strategic alliance, encouraging reverse innovation. The objective of this study is to identify an alliance strategy and alliance dynamics that encourage innovation of low-cost medical devices...master thesis 2020
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Willemsen, Mark (author)Introduction: Smart Medics Company is a startup from the Delft University of Technology, looking to bring an affordable Video laryngoscope (VL) into hospitals in low-resource regions. This research aims to seek the best suitable transparent material to act as a lens, sealing off a compartment containing an endoscope, as well as, bring forth a...master thesis 2020
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Łoin, Michal (author)Proper security mechanism are a crucial part of safe usage of Implantable Medical Devices. Multiple researchers presented various solutions to address this problem, basing them on different underlying principles. Within the scope of this thesis we perform a security analysis of the chosen authentication protocols. What is more, we present a new...master thesis 2020
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Siddiqi, M.A. (author), Serdijn, W.A. (author), Strydis, C. (author)The wireless capabilities of modern Implantable Medical Devices (IMDs) make them vulnerable to security attacks. One prominent attack, which has disastrous consequences for the patient’s wellbeing, is the battery Denial-of-Service attack whereby the IMD is occupied with continuous authentication requests from an adversary with the aim of...journal article 2020
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Tervoort, Tom (author), Tuler de Oliveira, M. (author), Pieters, W. (author), van Gelder, P.H.A.J.M. (author), Olabarriaga, Silvia Delgado (author), Marquering, Henk (author)Cyberattacks against healthcare institutions threaten patient care. The risk of being targeted by a damaging attack is increased when medical devices are used which rely on unmaintained legacy software that cannot be replaced and may have publicly known vulnerabilities. This review aims to provide insight into solutions presented in the...journal article 2020
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Henselmans, P.W.J. (author), Culmone, C. (author), Jager, D.J. (author), van Starkenburg, R.I.B. (author), Breedveld, P. (author)The fields of Minimally Invasive Surgery (MIS) and Natural Orifices Transluminal Endoscopic Surgery (NOTES) strive to reduce the level of invasiveness by entering the body through smaller incisions and natural orifices. Hyper-redundant snake-like instruments can help in this pursuit of reducing invasiveness. Such instruments can pass along...journal article 2020
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Sakes, A. (author), van de Steeg, Ivo A. (author), de Kater, E.P. (author), Posthoorn, P. (author), Scali, M. (author), Breedveld, P. (author)Currently existing tubular transportation systems for the extraction of large tissue masses during Minimal Invasive Surgery (MIS) are subjected to a large amount of operating limitations. In this study, a novel transportation mechanism (patented) was developed inspired by the egg-laying structure of wasps. The developed mechanism consists of...journal article 2020
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van der Plaats, Lisa (author)The quality of rigid endoscopes deteriorates during clinical use due to the sterilization process, mechanical forces and wear and tear during regular use. Regulations and standards on ensuring the quality of these instruments are currently non-existent or contain only qualitative measures, resulting in subjective examinations . Defective rigid...master thesis 2019
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Gurram, Nitin (author)The learning curve of novice surgeons takes about 25 surgeries to be proficient at the knee replacement procedure. So it is not just enough if we design efficient and more ergonomic surgical tools, it is also important to provide a learning platform for them to get better before they operate on a real patient. Although many training simulators...master thesis 2019
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Krijgsman, Laurens (author)The technology used in health care is one of the fastest developing fields in Precision Engineering. The main focus in this field is on the development of steerable, small dimensioned instruments. Using these, surgeries can be done with minimal damage to the patient, shorter hospital stay and more aesthetical healing.<br/>From the medical field...master thesis 2019