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Samenjo, K.T. (author), Oosting, R.M. (author), Bakker, C.A. (author), Diehl, J.C. (author)Healthcare facilities in low-resource settings in Sub-Saharan Africa are plagued<br/>with issues of non-functional and obsolete medical devices, which ultimately<br/>end up prematurely disposed of as waste. With increasing healthcare demands,<br/>stopping medical device disposal is imperative. One way to achieve this is<br/>to leverage circular...journal article 2023
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de Kater, E.P. (author), Müller, R. (author), Sakes, A. (author), Breedveld, P. (author)The fixation strength of pedicle screws could be increased by fixating along the much stronger cortical bone layer, which is not possible with the current rigid and straight bone drills. Inspired by the tsetse fly, a single-plane steerable bone drill was developed. The drill has a flexible transmission using two stacked leaf springs such that...journal article 2023
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Samenjo, K.T. (author), Ramanathan, Aparna (author), Gwer, Stephen Otieno (author), Bailey, Robert C. (author), Otieno, Fredrick Odhiambo (author), Koksal, Erin (author), Sprecher, Benjamin (author), Price, R.A. (author), Bakker, C.A. (author), Diehl, J.C. (author)Underfunded healthcare infrastructures in low-resource settings in sub-Saharan Africa have resulted in a lack of medical devices crucial to provide healthcare for all. A representative example of this scenario is medical devices to administer paracervical blocks during gynaecological procedures. Devices needed for this procedure are usually...journal article 2023
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Tesselaar, Izaka (author)Introduction – Cardiovascular diseases are the leading cause of death in the world with one in three succumbing to the disease. The most common cardiovascular disease is coronary artery disease, caused by atherosclerosis resulting in a build-up of plaque within the arteries. This plaque can progress into a vulnerable plaque, which has been...master thesis 2022
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Verberne, Yinte (author)The surgical procedure of tissue extraction from the human body for precautionary or curative measures is common in many medical fields. Currently, aspiration catheters are the golden standard, enabling removal by means of a suction force. By Sakes et al., an alternative mechanism is proposed, transporting tissue based on friction, inspired by...master thesis 2022
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Sakes, A. (author), Lageweg, M. (author), van Starkenburg, R.I.B. (author), Sontakke, S.S. (author), Spronck, J.W. (author)With the ongoing miniaturization of surgical instruments, the ability to apply large forces on tissues for resection becomes challenging and the risk of buckling becomes more real. In an effort to allow for high force application in slender instruments, in this study, we have investigated using a hydraulic pressure wave (COMSOL model) and...journal article 2022
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de Kuiper, Mike (author)Background: Colonoscopy is a successful screening method to prevent colorectal cancer (CRC). Biopsies are performed from suspicious tissue spots during the colonoscopic procedure to find cancerous polyps in an early stage of the disease. However, taking multiple biopsies is rather time-consuming and requires many repetitious actions from the...master thesis 2021
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van der Kroft, Sander (author)Millions of people around the world rely on kidney dialysis to replace the essential function of their kidneys. In order to receive dialysis, adequate access to the circulation is needed. The golden standard, the Arteriovenous Fistula (AVF), hasn’t really changed since the 1940’s and comes with disappointing patency and reintervention rates....master thesis 2021
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de Kater, E.P. (author), Sakes, A. (author), Bloemberg, J. (author), Jager, D.J. (author), Breedveld, P. (author)Tissue transport is a challenge during Minimally Invasive Surgery (MIS) with the current suction-based instruments as the increasing length and miniaturisation of the outer diameter requires a higher pressure. Inspired by the wasp ovipositor, a slender and bendable organ through which eggs can be transported, a flexible transport mechanism for...journal article 2021
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Schouten, Anneke (author)When in 2008 the financial crisis set it in Europe, consequences for the healthcare systems were inevitable (Parmar, Stavropoulou, & Ioannidis, 2016). Health budgets were reduced, and since the beginning of the crisis, 1.5 million additional people in Europe have had an unmet need for healthcare (A. Reeves, McKee, & Stuckler, 2015). A...master thesis 2020
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Willemsen, Mark (author)Introduction: Smart Medics Company is a startup from the Delft University of Technology, looking to bring an affordable Video laryngoscope (VL) into hospitals in low-resource regions. This research aims to seek the best suitable transparent material to act as a lens, sealing off a compartment containing an endoscope, as well as, bring forth a...master thesis 2020
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Sakes, A. (author), van de Steeg, Ivo A. (author), de Kater, E.P. (author), Posthoorn, P. (author), Scali, M. (author), Breedveld, P. (author)Currently existing tubular transportation systems for the extraction of large tissue masses during Minimal Invasive Surgery (MIS) are subjected to a large amount of operating limitations. In this study, a novel transportation mechanism (patented) was developed inspired by the egg-laying structure of wasps. The developed mechanism consists of...journal article 2020
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Gurram, Nitin (author)The learning curve of novice surgeons takes about 25 surgeries to be proficient at the knee replacement procedure. So it is not just enough if we design efficient and more ergonomic surgical tools, it is also important to provide a learning platform for them to get better before they operate on a real patient. Although many training simulators...master thesis 2019
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Krijgsman, Laurens (author)The technology used in health care is one of the fastest developing fields in Precision Engineering. The main focus in this field is on the development of steerable, small dimensioned instruments. Using these, surgeries can be done with minimal damage to the patient, shorter hospital stay and more aesthetical healing.<br/>From the medical field...master thesis 2019
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Mulckhuyse, Joppe (author)Objectives – Over the past decades, more and more cardiac diseases have been treated in interventional cardiology. Catheters are generally used to access the heart through the blood vessels. The previously developed steerable Sigma catheter at Delft University of Technology, tackles cable related challenges of conventional mechanically...master thesis 2019
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Sakes, A. (author), Grandia, Leander (author), Lether, Remie (author), Steenstra, Lukas (author), Valentijn, Maurice C. (author), Breedveld, P. (author), Spronck, J.W. (author)A major challenge during minimally invasive surgery is transfer of high forces through small, flexible instruments, such as needles and catheters, because of their low buckling resistance. In this study, we determined the feasibility of using a Newton's Cradle-inspired catheter (patented) to transfer high-force impulses. Exerting a high-force...journal article 2019
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Sakes, A. (author), Snaar, Kevin (author), Smit, G. (author), Witkamp, Arjen J. (author), Breedveld, P. (author)Background. The majority of the benign and malignant lesions in the breast arise from the ductal epithelium and terminal ductlobular unit. A minimally invasive procedure called ductoscopy is able to visualize these lesions as it inspects the ductal epithelium using a small micro-endoscope. Unfortunately, it is currently challenging to obtain...journal article 2018
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Sakes, A. (author), Nicolaï, Tjibbe (author), Karapanagiotis, Jordan (author), Breedveld, P. (author), Spronck, J.W. (author)Crossing highly calcified occlusions is technically challenging mainly due to guidewire buckling. In an effort to prevent buckling, a catheter that uses a dynamic impulse load is proposed. The proposed Wave catheter consists of an input plunger to generate an impulse at the handle, a hydraulic pressure wave confined within a ∅2 mm catheter to...journal article 2018
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Sakes, A. (author), Hovland, Kevin (author), Smit, G. (author), Geraedts, Jo M.P. (author), Breedveld, P. (author)In current bipolar electrosurgical instruments, a high frequency electrical sinusoidal wave is passed through the patient's body from an active electrode to the return electrode to cut, coagulate, or desiccate tissues. Even though current bipolar electrosurgical instruments have proven effective in minimizing blood loss, advancement is needed...journal article 2018
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Loeve, A.J. (author)In 2015, a multi-resistant Klebsiella pneumonia bacteria (“MR Klebsiella”) was found in two Olympus video duodenoscopes of the type TJF-Q180V in the Utrecht University Medical Center (“UMC Utrecht”) after the culturing of flush samples (sterile physiological saline), which were sent through the suction and biopsy channels. This report describes...report 2017
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