Models of electroporation and the associated transmembrane molecular transport should be revisited

Electroporation has become a powerful tool for nonviral delivery of various biomolecules such as nucleic acids, proteins, and chemotherapeutic drugs to virtually any living cell by exposing the cell membrane to an intense pulsed electric field. Different multiphysics and multiscale models have been developed to describe the phenomenon of...

Multi-Physics Driven Electromigration Study: Multi-Scale Modeling and Experiment

This dissertation presents a comprehensive and integrated study, including theory development, numerical simulation and experiment, for multi-physics driven electromigration in microelectronics. Multi-scale methodologies from atomistic modeling to continuum theory-based simulation have been developed. Moreover, extensive experimental testing,...

Numerical and Experimental Investigation of Hygrothermal Aging in Laminated Composites

Although being a crucial step in structural design of laminated composites, prediction of their long-term mechanical performance remains a challenging task for which no comprehensive and reliable solution is currently available. Nevertheless, structures such as wind turbine blades, of which laminated composites constitute the main load bearing...